[HTML][HTML] The role of maternal immune activation in immunological and neurological pathogenesis of autism

K Liu, Y Huang, Y Zhu, Y Zhao, X Kong - Journal of Neurorestoratology, 2023 - Elsevier
The growing body of evidence associates infections during pregnancy and other
inflammatory insults with developing neurodevelopmental and neurodevelopmental …

Blockage of VEGF function by bevacizumab alleviates early-stage cerebrovascular dysfunction and improves cognitive function in a mouse model of Alzheimer's …

M Zhang, Z Zhang, H Li, Y Xia, M Xing, C Xiao… - Translational …, 2024 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disorder and the predominant
type of dementia worldwide. It is characterized by the progressive and irreversible decline of …

Age, brain region, and gene dosage-differential transcriptomic changes in Shank3-mutant mice

T Yoo, YE Yoo, H Kang, E Kim - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Shank3 is an abundant excitatory postsynaptic scaffolding protein implicated in various
neurodevelopmental disorders, including autism spectrum disorder (ASD), Phelan …

[HTML][HTML] The Use of Nutraceutical and Pharmacological Strategies in Murine Models of Autism Spectrum Disorder

M Bonetti, E Borsani, F Bonomini - Cells, 2024 - mdpi.com
Autism spectrum disorder (ASD) is a common neurodevelopmental condition mainly
characterized by both a scarce aptitude for social interactions or communication and …

Sex-specific transcriptomic signatures in brain regions critical for neuropathic pain-induced depression

W Dai, S Huang, Y Luo, X Cheng, P Xia… - Frontiers in Molecular …, 2022 - frontiersin.org
Neuropathic pain is a chronic debilitating condition with a high comorbidity with depression.
Clinical reports and animal studies have suggested that both the medial prefrontal cortex …

Enhanced fear limits behavioral flexibility in Shank2-deficient mice

M Yun, E Kim, MW Jung - Molecular Autism, 2022 - Springer
Background A core symptom of autism spectrum disorder (ASD) is repetitive and restrictive
patterns of behavior. Cognitive inflexibility has been proposed as a potential basis for these …

Brain region and gene dosage-differential transcriptomic changes in Shank2-mutant mice

YE Yoo, T Yoo, H Kang, E Kim - Frontiers in Molecular Neuroscience, 2022 - frontiersin.org
Shank2 is an abundant excitatory postsynaptic scaffolding protein that has been implicated
in various neurodevelopmental and psychiatric disorders, including autism spectrum …

Inhibition of the Wnt/β‑catenin signaling pathway and SOX9 by XAV939 did not alleviate inflammation in a dextran sulfate sodium‑induced ulcerative colitis model

SJ Liang, K Wang, DB Mao… - Experimental and …, 2024 - spandidos-publications.com
The Wnt/β-catenin signaling pathway has been reported to be hyperactivated during the
pathogenesis of ulcerative colitis (UC). The present study aimed to explore the therapeutic …

The role of synaptic and extrasynaptic NMDA receptors imbalance and mitochondrial permeability in hit-induced brain trauma

RAM Guzmán - 2023 - search.proquest.com
Los receptores del tipo N-metil-D-Aspartato (NMDA) son actores moleculares clave tanto en
procesos de plasticidad sináptica como en mecanismos de muerte neuronal en el cerebro …

Enhanced fear limits behavioral flexibility in a mouse model of autism spectrum disorder

M Yun, E Kim, MW Jung - 2022 - researchsquare.com
Background: A core symptom of autism spectrum disorder (ASD) is repetitive and restrictive
patterns of behavior. Cognitive inflexibility has been proposed as a potential basis for these …