Inflammatory response to different toxins in experimental sepsis models

K Dickson, C Lehmann - International journal of molecular sciences, 2019 - mdpi.com
Sepsis is defined as life-threatening organ dysfunction caused by the dysregulated host
response to infection. Despite serious mortality and morbidity, no sepsis-specific drugs exist …

Role of ion channels and transporters in cell migration

A Schwab, A Fabian, PJ Hanley… - Physiological …, 2012 - journals.physiology.org
Cell motility is central to tissue homeostasis in health and disease, and there is hardly any
cell in the body that is not motile at a given point in its life cycle. Important physiological …

[HTML][HTML] Molecular mechanisms governing aquaporin relocalisation

A Markou, L Unger, M Abir-Awan, A Saadallah… - … et Biophysica Acta (BBA …, 2022 - Elsevier
The aquaporins (AQPs) form a family of integral membrane proteins that facilitate the
movement of water across biological membrane by osmosis, as well as facilitating the …

On the origin of low-density neutrophils

M Hassani, P Hellebrekers, N Chen… - Journal of Leukocyte …, 2020 - academic.oup.com
Here we elaborate on the origin of low (er)-density neutrophils (LDNs) to better understand
the variation found in literature. Supplemented with original data, we test the hypothesis that …

Low-density neutrophils in healthy individuals display a mature primed phenotype

C Blanco-Camarillo, OR Alemán… - Frontiers in …, 2021 - frontiersin.org
Neutrophils are the most abundant leukocytes in human peripheral blood, comprising about
70% of all leukocytes. They are regarded as the first line of defense of the innate immune …

Aquaporin-9 facilitates membrane transport of hydrogen peroxide in mammalian cells

S Watanabe, CS Moniaga, S Nielsen… - Biochemical and …, 2016 - Elsevier
Abstract Aquaporin (AQP) 9, a member of the transmembrane water channel family, is
defined as a water/glycerol transporting protein. Some AQPs including AQP3 and AQP8 …

Nuclear pore permeability and fluid flow are modulated by its dilation state

PC Hoffmann, H Kim, A Obarska-Kosinska, JP Kreysing… - Molecular Cell, 2024 - cell.com
Changing environmental conditions necessitate rapid adaptation of cytoplasmic and nuclear
volumes. We use the slime mold Dictyostelium discoideum, known for its ability to tolerate …

Quorum sensing communication between bacteria and human cells: signals, targets, and functions

A Holm, E Vikström - Frontiers in plant science, 2014 - frontiersin.org
Both direct and long-range interactions between pathogenic Pseudomonas aeruginosa
bacteria and their eukaryotic hosts are important in the outcome of infections. For cell-to-cell …

Immune response in severe and non-severe coronavirus disease 2019 (COVID-19) infection: a mechanistic landscape

K Mukund, P Nayak, C Ashokkumar, S Rao… - Frontiers in …, 2021 - frontiersin.org
The mechanisms underlying the immune remodeling and severity response in coronavirus
disease 2019 (COVID-19) are yet to be fully elucidated. Our comprehensive integrative …

Legacy and emerging per-and polyfluoroalkyl substances suppress the neutrophil respiratory burst

DW Phelps, AI Palekar, HE Conley… - Journal of …, 2023 - Taylor & Francis
Per-and polyfluoroalkyl substances (PFASs) are used in a multitude of processes and
products, including nonstick coatings, food wrappers, and fire-fighting foams. These …