Diabetic macular edema (DME) is the major cause of vision loss in diabetic persons.
Alteration of the blood–retinal barrier is the hallmark of this disease, characterized by …

Diabetic retinopathy (DR) is a leading cause of blindness. It has long been regarded as
vascular disease, but work in the past years has shown abnormalities also in the neural …

The complex pathology of diabetic retinopathy (DR) affects both vascular and neural tissue.
The characteristics of neurodegeneration are well-described in animal models but have …

Aims/hypothesis Levels of neutrophil elastase, a serine protease secreted by neutrophils,
are elevated in diabetes. The purpose of this study was to determine whether neutrophil …

Diabetic retinopathy (DR) is a leading cause of blindness in working age adults. DR has non-
proliferative stages, characterized in part by retinal neuroinflammation and ischemia, and …

The breakdown of the inner endothelial blood–retinal barrier (BRB) and subsequent retinal
vascular leakage are the main causes of vision loss due to diabetic retinopathy (DR) …

Purpose.: To test the hypothesis that in a mouse model of diabetic retinopathy, oxidative
stress is linked with impaired light-evoked expansion of choroidal thickness and subretinal …

Purpose: To test the hypothesis that mitochondrial respiration contributes to local changes in
hydration involved in phototransduction-driven expansion of outer retina, as measured by …

Background Diabetic retinopathy (DR) is the second commonest microvascular complication
of diabetes mellitus. It is characterized by chronic inflammation and angiogenesis. Palm oil …

Aims/hypothesis Diabetic retinopathy is a severe complication of diabetes mellitus that often
leads to blindness. Because the pathophysiology of diabetic retinopathy is not fully …