[HTML][HTML] Global survey of the omega-3 fatty acids, docosahexaenoic acid and eicosapentaenoic acid in the blood stream of healthy adults

KD Stark, ME Van Elswyk, MR Higgins… - Progress in lipid …, 2016 - Elsevier
Studies reporting blood levels of the omega-3 polyunsaturated fatty acids, eicosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA), were systematically identified in order to …

Analytical methods in untargeted metabolomics: state of the art in 2015

A Alonso, S Marsal, A Julià - Frontiers in bioengineering and …, 2015 - frontiersin.org
Metabolomics comprises the methods and techniques that are used to measure the small
molecule composition of biofluids and tissues, and is actually one of the most rapidly …

Genome-wide patterns of selection in 230 ancient Eurasians

I Mathieson, I Lazaridis, N Rohland, S Mallick… - Nature, 2015 - nature.com
Ancient DNA makes it possible to observe natural selection directly by analysing samples
from populations before, during and after adaptation events. Here we report a genome-wide …

Systematic identification of trans eQTLs as putative drivers of known disease associations

HJ Westra, MJ Peters, T Esko, H Yaghootkar… - Nature …, 2013 - nature.com
Identifying the downstream effects of disease-associated SNPs is challenging. To help
overcome this problem, we performed expression quantitative trait locus (eQTL) meta …

Metabolism and functional effects of plant-derived omega-3 fatty acids in humans

EJ Baker, EA Miles, GC Burdge, P Yaqoob… - Progress in lipid …, 2016 - Elsevier
Alpha-linolenic acid (ALA) is an essential fatty acid and the substrate for the synthesis of
longer-chain, more unsaturated ω-3 fatty acids, eicosapentaenoic acid (EPA) …

Fatty acid desaturases, polyunsaturated fatty acid regulation, and biotechnological advances

JM Lee, H Lee, SB Kang, WJ Park - Nutrients, 2016 - mdpi.com
Polyunsaturated fatty acids (PUFAs) are considered to be critical nutrients to regulate human
health and development, and numerous fatty acid desaturases play key roles in synthesizing …

Comprehensive profiling of plasma fatty acid concentrations in young healthy Canadian adults

SA Abdelmagid, SE Clarke, DE Nielsen, A Badawi… - PloS one, 2015 - journals.plos.org
Circulating fatty acids (FA) are associated with a multitude of chronic diseases. However, a
major gap in establishing such relationships is the lack of accepted fatty acid reference …

[HTML][HTML] Impact of maternal diet on human milk composition and neurological development of infants

SM Innis - The American journal of clinical nutrition, 2014 - Elsevier
Maternal nutrition has little or no effect on many nutrients in human milk; for others, human
milk may not be designed as a primary nutritional source for the infant; and for a few …

Gamma-linolenic acid, dihommo-gamma linolenic, eicosanoids and inflammatory processes

S Sergeant, E Rahbar, FH Chilton - European journal of pharmacology, 2016 - Elsevier
Abstract Gamma-linolenic acid (GLA, 18: 3n-6) is an omega-6 (n-6), 18 carbon (18C-)
polyunsaturated fatty acid (PUFA) found in human milk and several botanical seed oils and …

Methylation of ELOVL2 gene as a new epigenetic marker of age

P Garagnani, MG Bacalini, C Pirazzini, D Gori… - Aging cell, 2012 - Wiley Online Library
The discovery of biomarkers able to predict biological age of individuals is a crucial goal in
aging research. Recently, researchers' attention has turn toward epigenetic markers of …