Ultrasound‐controlled drug release and drug activation for cancer therapy

L Tu, Z Liao, Z Luo, YL Wu, A Herrmann, S Huo - Exploration, 2021 - Wiley Online Library
Traditional chemotherapy suffers from severe toxicity and side effects that limit its maximum
application in cancer therapy. To overcome this challenge, an ideal treatment strategy would …

Chemo-physical Strategies to Advance the in Vivo Functionality of Targeted Nanomedicine: The Next Generation

J Li, K Kataoka - Journal of the American Chemical Society, 2020 - ACS Publications
The past few decades have witnessed an evolution of nanomedicine from biologically inert
entities to more smart systems, aimed at advancing in vivo functionality. However, we should …

Ultrasound-mediated nano drug delivery for treating cancer: Fundamental physics to future directions

FM Kashkooli, A Jakhmola, TK Hornsby… - Journal of Controlled …, 2023 - Elsevier
The application of biocompatible nanocarriers in medicine has provided several benefits
over conventional treatment methods. However, achieving high treatment efficacy and deep …

Integrating artificial intelligence and nanotechnology for precision cancer medicine

O Adir, M Poley, G Chen, S Froim, N Krinsky… - Advanced …, 2020 - Wiley Online Library
Artificial intelligence (AI) and nanotechnology are two fields that are instrumental in realizing
the goal of precision medicine—tailoring the best treatment for each cancer patient. Recent …

Lipid-based drug delivery systems in cancer therapy: what is available and what is yet to come

P Yingchoncharoen, DS Kalinowski… - Pharmacological …, 2016 - ASPET
Cancer is a leading cause of death in many countries around the world. However, the
efficacy of current standard treatments for a variety of cancers is suboptimal. First, most …

Advanced targeted therapies in cancer: Drug nanocarriers, the future of chemotherapy

E Pérez-Herrero, A Fernández-Medarde - European journal of …, 2015 - Elsevier
Cancer is the second worldwide cause of death, exceeded only by cardiovascular diseases.
It is characterized by uncontrolled cell proliferation and an absence of cell death that, except …

Stimuli-responsive polymeric micelles for drug delivery and cancer therapy

Q Zhou, L Zhang, TH Yang, H Wu - International journal of …, 2018 - Taylor & Francis
Polymeric micelles (PMs) have been widely investigated as nanocarriers for drug delivery
and cancer treatments due to their excellent physicochemical properties, drug loading and …

Nanomedicine in cancer therapy: challenges, opportunities, and clinical applications

A Wicki, D Witzigmann, V Balasubramanian… - Journal of controlled …, 2015 - Elsevier
Cancer is a leading cause of death worldwide. Currently available therapies are inadequate
and spur demand for improved technologies. Rapid growth in nanotechnology towards the …

Multifunctional, stimuli-sensitive nanoparticulate systems for drug delivery

VP Torchilin - Nature reviews Drug discovery, 2014 - nature.com
The use of nanoparticulate pharmaceutical drug delivery systems (NDDSs) to enhance the
in vivo effectiveness of drugs is now well established. The development of multifunctional …

Stimuli-responsive nanocarriers for drug delivery

S Mura, J Nicolas, P Couvreur - Nature materials, 2013 - nature.com
Spurred by recent progress in materials chemistry and drug delivery, stimuli-responsive
devices that deliver a drug in spatial-, temporal-and dosage-controlled fashions have …