Septins are an integral component of the cytoskeleton, assembling into higher-order
oligomers and filamentous polymers that associate with actin filaments, microtubules and …

Cellular secretion depends on exocytosis of secretory vesicles and discharge of vesicle
contents. Actin and myosin are essential for pre-fusion and post-fusion stages of exocytosis …

During preimplantation development, mouse embryos form a fluid-filled lumen. Pressurized
fluid fractures cell–cell contacts and accumulates into pockets, which coarsen into a single …

Exocrine secretion commonly employs micron-scale vesicles that fuse to a limited apical
surface, presenting an extreme challenge for maintaining membrane homeostasis. Using …

Tissues are heterogeneous with respect to cellular and non-cellular components and in the
dynamic interactions between these elements. To study the behaviour and fate of individual …

Fluorescence recovery after photobleaching (FRAP) has emerged as one of the most widely
utilized techniques to quantify binding and diffusion kinetics of biomolecules in biophysics …

Membrane remodeling drives a broad spectrum of cellular functions, and it is regulated
through mechanical forces exerted on the membrane by cytoplasmic complexes. Here, we …

During embryonic development, cells shape our body, which is mostly made up of water. It is
often forgotten that some of this water is found in intercellular fluid, which, for example …

Nematocysts are generated by secretion of proteins into a post-Golgi compartment. They
consist of a capsule that elongates into a long tube, which is coiled inside the capsule matrix …

During morphogenesis, epithelial tissues reshape and expand to cover the body and
organs. The molecular mechanisms of this deformability remain elusive. Here, we …