Endothelial cell metabolism in normal and diseased vasculature

G Eelen, P De Zeeuw, M Simons… - Circulation research, 2015 - Am Heart Assoc
Higher organisms rely on a closed cardiovascular circulatory system with blood vessels
supplying vital nutrients and oxygen to distant tissues. Not surprisingly, vascular pathologies …

Brothers in arms: ABCA1-and ABCG1-mediated cholesterol efflux as promising targets in cardiovascular disease treatment

SJCM Frambach, R de Haas, JAM Smeitink… - Pharmacological …, 2020 - Elsevier
Atherosclerosis is a leading cause of cardiovascular disease worldwide, and
hypercholesterolemia is a major risk factor. Preventive treatments mainly focus on the …

An integrated lipidomics and metabolomics reveal nephroprotective effect and biochemical mechanism of Rheum officinale in chronic renal failure

ZH Zhang, ND Vaziri, F Wei, XL Cheng, X Bai… - Scientific reports, 2016 - nature.com
Chronic renal failure (CRF) is a major public health problem worldwide. Earlier studies have
revealed salutary effects of rhubarb extracts in CRF. In this study, we employed lipidomic …

Lipidomics Biomarkers of Diet-Induced Hyperlipidemia and Its Treatment with Poria cocos

H Miao, YH Zhao, ND Vaziri, DD Tang… - Journal of agricultural …, 2016 - ACS Publications
Hyperlipidemia is a major cause of atherosclerotic cardiovascular disease. Poria cocos (PC)
is a medicinal product widely used in Asia. This study was undertaken to define the …

[HTML][HTML] Possible mechanisms of cholesterol elevation aggravating COVID-19

Y Tang, L Hu, Y Liu, B Zhou, X Qin, J Ye… - … journal of medical …, 2021 - ncbi.nlm.nih.gov
Importance: Despite the availability of a vaccine against the severe acute respiratory
syndrome-coronavirus-2 (SARS-CoV-2), humans will have to live with this virus and the after …

A review on the traditional Chinese medicinal herbs and formulae with hypolipidemic effect

TT Sham, CO Chan, YH Wang, JM Yang… - BioMed Research …, 2014 - Wiley Online Library
Hyperlipidemia, characterized by the abnormal blood lipid profiles, is one of the dominant
factors of many chronic diseases such as diabetes, obesity, and cardiovascular diseases …

Gougunao tea polysaccharides ameliorate high-fat diet-induced hyperlipidemia and modulate gut microbiota

Q Deng, W Wang, L Zhang, L Chen, Q Zhang… - Food & Function, 2023 - pubs.rsc.org
Many natural polysaccharides have been proven to have ameliorative effects on high-fat diet-
induced hyperlipidemia with fewer side effects. However, similar data on Gougunao tea …

Risk identification and possible countermeasures for muscle adverse effects during statin therapy

P Magni, C Macchi, B Morlotti, CR Sirtori… - European journal of …, 2015 - Elsevier
The use of statins for cardiovascular disease prevention is clearly supported by clinical
evidence. However, in January 2014 the US Food and Drug Administration released an …

Gut microbiota mediates positive effects of liraglutide on dyslipidemia in mice fed a high-fat diet

L Zhao, Y Qiu, P Zhang, X Wu, Z Zhao, X Deng… - Frontiers in …, 2022 - frontiersin.org
Except for improving glycemic control, liraglutide, one of the glucagon-like peptide-1
receptor agonists, has exerted promising therapeutic effects for dyslipidemia. It has been …

Effect of Phenolic Compounds from Cymbopogon citratus (DC) Stapf. Leaves on Micellar Solubility of Cholesterol

S Da Ressurreição, S Pedreiro, MT Batista… - Molecules, 2022 - mdpi.com
Dyslipidemias are one of the risk factors for cardiovascular diseases, the leading cause of
death and hospitalization worldwide. One way to control cholesterol levels is to control the …