The thalamus is a small, bilateral structure in the diencephalon that integrates signals from
many areas of the CNS. This critical anatomical position allows the thalamus to influence …

There have been a number of advances in the search for the neural correlates of
consciousness—the minimum neural mechanisms sufficient for any one specific conscious …

Episodic memory-based decision-making requires top-down medial prefrontal cortex and
hippocampal interactions. This integrated prefrontal-hippocampal memory state is thought to …

Functional MRI and electrophysiology studies suggest that consciousness depends on large-
scale thalamocortical and corticocortical interactions. However, it is unclear how neurons in …

Functions of the neocortex depend on its bidirectional communication with the thalamus, via
cortico-thalamo-cortical (CTC) loops. Recent work dissecting the synaptic connectivity in …

Several challenges to current views of thalamocortical processing are offered here.
Glutamatergic pathways in thalamus and cortex are divided into two distinct classes: driver …

Similarities in neocortical circuit organization across areas and species suggest a common
strategy to process diverse types of information, including sensation from diverse modalities …

The thalamus is globally connected with distributed cortical regions, yet the functional
significance of this extensive thalamocortical connectivity remains largely unknown. By …

This Perspective considers the influential notion of a canonical (cortical) microcircuit in light
of recent theories about neuronal processing. Specifically, we conciliate quantitative studies …

Cognition results from interactions among functionally specialized but widely distributed
brain regions; however, neuroscience has so far largely focused on characterizing the …