Tuberculosis is a deadly communicable disease caused by the bacillus Mycobacterium
tuberculosis (MTB), and pulmonary tuberculosis accounts for over 80% of the total cases …

Tuberculosis regimens currently applied in clinical practice require months of multidrug
therapy, which imposes a major challenge of patient compliance and drug resistance …

The aim of this study was to investigate the potential of human serum albumin (HSA) as a
solubilising agent/drug delivery vehicle for pulmonary administration of antimycobacterial …

Background Although it is a preventable and treatable disease, tuberculosis remains a
major medical and public health problem throughout the world. The control and elimination …

An exploration of the chemical space around a 2, 5-dimethylpyrrole scaffold of antitubercular
hit compound 1 has led to the identification of new derivatives active against Mycobacterium …

Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), has surpassed
HIV/AIDS as the leading cause of death from a single infectious agent. The increasing …

Despite the increasing need of new antituberculosis drugs, the number of agents approved
for the market has fallen to an all-time low. In response to the emerging drug resistance …

Tuberculosis (TB) continues to be a major health hazard worldwide due to the resurgence of
drug discovery strains of Mycobacterium tuberculosis (Mtb) and co-infection. For decades …

Mycobacterium tuberculosis is a causative agent for the world threatening infectious disease
known as tuberculosis. M. tuberculosis is also referred as Koch's bacillus as it was first …

A series of indolyl-3-methyleneamines incorporating lipophilic side chains were designed
through a structural rigidification approach and synthesized for investigation as new …