Mitochondrial mutations and mitoepigenetics: Focus on regulation of oxidative stress-induced responses in breast cancers

K Chen, P Lu, NM Beeraka, OA Sukocheva… - Seminars in cancer …, 2022 - Elsevier
Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-developing
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …

Polycystic ovary syndrome and mitochondrial dysfunction

J Zhang, Y Bao, X Zhou, L Zheng - Reproductive Biology and …, 2019 - Springer
Polycystic ovary syndrome (PCOS) is a prevalent hormonal disorder of premenopausal
women worldwide and is characterized by reproductive, endocrine, and metabolic …

Measuring biomarkers in wastewater as a new source of epidemiological information: Current state and future perspectives

E Gracia-Lor, S Castiglioni, R Bade, F Been… - Environment …, 2017 - Elsevier
The information obtained from the chemical analysis of specific human excretion products
(biomarkers) in urban wastewater can be used to estimate the exposure or consumption of …

[HTML][HTML] A review of the epidemiology of breast cancer in Asia: focus on risk factors

HJ Youn, W Han - Asian Pacific journal of cancer prevention …, 2020 - ncbi.nlm.nih.gov
Methods: We conducted a PubMed search on 15 March 2016, for journal articles published
in English between 2011 and 2016, which reported data for human subjects in Asia with a …

Mitochondria in tumour progression: a network of mtDNA variants in different types of cancer

GC Cavalcante, Â Ribeiro-dos-Santos, GS de Araújo - BMC genomic data, 2022 - Springer
Background Mitochondrial participation in tumorigenesis and metastasis has been studied
for many years, but several aspects of this mechanism remain unclear, such as the …

Mitochondrial DNA mutation analysis in breast cancer: shifting from germline heteroplasmy toward homoplasmy in tumors

CJ Pérez-Amado, H Tovar, L Gómez-Romero… - Frontiers in …, 2020 - frontiersin.org
Studies have suggested a potential role of somatic mitochondrial mutations in cancer
development. To analyze the landscape of somatic mitochondrial mutation in breast cancer …

Impact of mitochondrial DNA copy number and displacement loop alterations on polycystic ovary syndrome risk in south Indian women

TV Reddy, S Govatati, M Deenadayal, S Sisinthy… - Mitochondrion, 2019 - Elsevier
Sequencing of mitochondrial displacement-loop (D-loop) of polycystic ovary syndrome
(PCOS) patients and (n= 118) and controls (n= 114) of south Indian origin showed …

Understanding mitochondrial polymorphisms in cancer

KM Bussard, LD Siracusa - Cancer Research, 2017 - AACR
Alterations in mitochondrial DNA (mtDNA) were once thought to be predominantly
innocuous to cell growth. Recent evidence suggests that mtDNA undergo naturally occurring …

Overview of mitochondrial germline variants and mutations in human disease: Focus on breast cancer

S Jiménez-Morales… - International …, 2018 - spandidos-publications.com
High lactate production in cells during growth under oxygen-rich conditions (aerobic
glycolysis) is a hallmark of tumor cells, indicating the role of mitochondrial function in …

A novel DNA biosensor using a ferrocenyl intercalator applied to the potential detection of human population biomarkers in wastewater

Z Yang, MA d'Auriac, S Goggins… - … science & technology, 2015 - ACS Publications
A new label-free electrochemical DNA (E-DNA) biosensor using a custom synthesized
ferrocenyl (Fc) double-stranded DNA intercalator as a redox marker is presented. Single …