Background. Infant and under-5 childhood mortality rates in developing countries have
declined significantly in the past 2 to 3 decades. However, 2 critical indicators, maternal and …

All malaria infections are harmful to both the pregnant mother and the developing fetus. One
in ten maternal deaths in malaria endemic countries are estimated to result from …

In this review we examine the available information on the safety of antimalarials in
pregnancy, from both animal and human studies. The antimalarials that can be used in …

Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Objective To determine the pharmacokinetic properties of artemether and lumefantrine (AL)
in pregnant women with recrudescent uncomplicated multi-drug resistant falciparum …

In areas where multidrug-resistant Plasmodium falciparum (MDR-Pf) is prevalent, only
quinine is known to be safe and effective in pregnant women. On the western border of …

In all malarious areas, infection by any of the main human plasmodial species during
pregnancy is detrimental to the mother and the fetus. These potentially fatal infections must …

Background Artemisinin derivatives are a relatively new group of drugs with antimalarial
properties. As resistance to other antimalarial drugs continues to increase, artemisinin drugs …

Background An increasing number of countries in sub-Saharan Africa are changing to
artemisinins combination therapy (ACT) as first or second line treatment for malaria. There is …

Falciparum malaria is an important cause of maternal, perinatal and neonatal morbidity in
high transmission settings in Sub-Saharan Africa. Intermittent preventive treatment with …