ABSTRACT Introduction: Cell penetrating peptides (CPPs) known as protein translocation
domains (PTD), membrane translocating sequences (MTS), or Trojan peptides (TP) are able …

Cell penetrating peptides (CPPs) are short amphipathic and cationic peptides that are
rapidly internalized across cell membranes. They can be used to deliver molecular cargo …

Leishmania parasites are well adapted to initiate infection, resist the onslaught of innate
immunity and achieve a state of long‐lived persistence. In recent years, the tools available to …

Background Leishmania infantum is the etiological agent of zoonotical visceral
leishmaniasis in the Mediterranean basin. A recent outbreak in humans has been recently …

The most dangerous form of leishmaniasis is Visceral leishmaniasis (VL). The elimination of
VL depends not only on agent treatments but also on effective vaccines against Leishmania …

There is no effective vaccine for the prevention and elimination of leishmaniasis. For this
reason, we assessed the protective effects of DNA vaccines containing Le IF, TSA genes …

Demands for effective vaccines to control parasitic diseases of humans and livestock have
been recently exacerbated by the development of resistance of most pathogenic parasites to …

DNA based immunization works well in animal models for the prevention and induction of
both humoral and cell-mediated immune responses1. Human papillomavirus type16 (HPV …

Gene therapy is the process of treating a particular disease through the introduction of
genetic material in order to elicit a therapeutic benefit [Stone, 2010]. The defective gene of a …

Chagas disease caused by protozoan parasite Trypanosoma cruzi is endemic disease in
South and Central American countries but due to migrating human populations it has shown …