Updates from the 2020 World Health Organization classification of soft tissue and bone tumours
WJ Anderson, LA Doyle - Histopathology, 2021 - Wiley Online Library
The fifth edition of the World Health Organization (WHO) classification of soft tissue and
bone tumours was published in May 2020. This 'Blue Book', which is also available digitally …
bone tumours was published in May 2020. This 'Blue Book', which is also available digitally …
The current landscape of rhabdomyosarcomas: an update
J Leiner, F Le Loarer - Virchows Archiv, 2020 - Springer
Rhabdomyosarcomas are malignancies associated with a rhabdomyoblastic phenotype
which can be demonstrated morphologically or by immunohistochemistry for MYOD1 and …
which can be demonstrated morphologically or by immunohistochemistry for MYOD1 and …
[HTML][HTML] A subset of epithelioid and spindle cell rhabdomyosarcomas is associated with TFCP2 fusions and common ALK upregulation
F Le Loarer, AHG Cleven, C Bouvier, MP Castex… - Modern Pathology, 2020 - Elsevier
Rhabdomyosarcomas with TFCP2 fusions represent an emerging subtype of tumors, initially
discovered by RNA-sequencing. We report herein the clinicopathological, transcriptional …
discovered by RNA-sequencing. We report herein the clinicopathological, transcriptional …
Head and neck rhabdomyosarcoma with TFCP2 fusions and ALK overexpression: a clinicopathological and molecular analysis of 11 cases
B Xu, AJH Suurmeijer, NP Agaram, L Zhang… - …, 2021 - Wiley Online Library
Aims Primary intraosseous rhabdomyosarcoma (RMS) is a rare entity defined by
EWSR1/FUS–TFCP2 or, less commonly, MEIS1–NCOA2 fusions. The lesions often show a …
EWSR1/FUS–TFCP2 or, less commonly, MEIS1–NCOA2 fusions. The lesions often show a …
Expanding the spectrum of intraosseous rhabdomyosarcoma: correlation between 2 distinct gene fusions and phenotype
NP Agaram, L Zhang, YS Sung… - The American journal …, 2019 - journals.lww.com
Primary intraosseous rhabdomyosarcomas (RMSs) are extremely rare. Recently 2 studies
reported 4 cases of primary intraosseous RMS with EWSR1/FUS-TFCP2 gene fusions …
reported 4 cases of primary intraosseous RMS with EWSR1/FUS-TFCP2 gene fusions …
[HTML][HTML] Molecular testing of rhabdomyosarcoma in clinical trials to improve risk stratification and outcome: A consensus view from European paediatric Soft tissue …
S Hettmer, CM Linardic, A Kelsey, ER Rudzinski… - European Journal of …, 2022 - Elsevier
Rhabdomyosarcomas (RMSs) are the most common soft tissue sarcomas in
children/adolescents less than 18 years of age with an annual incidence of 1–2/million …
children/adolescents less than 18 years of age with an annual incidence of 1–2/million …
[HTML][HTML] Fusion-driven spindle cell rhabdomyosarcomas of bone and soft tissue: a clinicopathologic and molecular genetic study of 25 cases
The evolving classification of rhabdomyosarcoma (RMS) now includes spindle cell RMS
(SRMS). Bone/soft tissue SRMS often harbor TFCP2, or less often MEIS1 rearrangements …
(SRMS). Bone/soft tissue SRMS often harbor TFCP2, or less often MEIS1 rearrangements …
Update from the 5th edition of the World Health Organization classification of head and neck tumors: soft tissue tumors
VY Jo, EG Demicco - Head and Neck Pathology, 2022 - Springer
The fifth (5th) edition of the World Health Organization (WHO) Classification of Head and
Neck Tumors introduces a new chapter dedicated to soft tissue neoplasms commonly …
Neck Tumors introduces a new chapter dedicated to soft tissue neoplasms commonly …
Epithelioid and spindle cell rhabdomyosarcoma with FUS-TFCP2 or EWSR1-TFCP2 fusion: report of two cases
JSA Chrisinger, B Wehrli, BC Dickson, S Fasih… - Virchows Archiv, 2020 - Springer
Abstract The WHO Classification of Tumors of Soft Tissue and Bone divides
rhabdomyosarcoma (RMS) into alveolar, embryonal, pleomorphic, and spindle …
rhabdomyosarcoma (RMS) into alveolar, embryonal, pleomorphic, and spindle …
Mesenchymal tumors with EWSR1 gene rearrangements
K Thway, C Fisher - Surgical Pathology Clinics, 2019 - surgpath.theclinics.com
Among the various genes that can be rearranged in soft tissue neoplasms associated with
nonrandom chromosomal translocations, EWSR1 is the most frequent one to partner with …
nonrandom chromosomal translocations, EWSR1 is the most frequent one to partner with …