[HTML][HTML] Tendon injury and repair–A perspective on the basic mechanisms of tendon disease and future clinical therapy

JG Snedeker, J Foolen - Acta biomaterialia, 2017 - Elsevier
Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

Adenomyosis: mechanisms and pathogenesis

J Zhai, S Vannuccini, F Petraglia… - Seminars in …, 2020 - thieme-connect.com
Adenomyosis is a common disorder of the uterus, and is associated with an enlarged uterus,
heavy menstrual bleeding (HMB), pelvic pain, and infertility. It is characterized by …

Pathogenesis of tendinopathies: inflammation or degeneration?

M Abate, K Gravare Silbernagel, C Siljeholm… - Arthritis research & …, 2009 - Springer
The intrinsic pathogenetic mechanisms of tendinopathies are largely unknown and whether
inflammation or degeneration has the prominent role is still a matter of debate. Assuming …

Mechanosensitive mechanisms in transcriptional regulation

A Mammoto, T Mammoto, DE Ingber - Journal of cell science, 2012 - journals.biologists.com
Transcriptional regulation contributes to the maintenance of pluripotency, self-renewal and
differentiation in embryonic cells and in stem cells. Therefore, control of gene expression at …

The pathogenesis of adenomyosis vis-à-vis endometriosis

SW Guo - Journal of clinical medicine, 2020 - mdpi.com
Adenomyosis is used to be called endometriosis interna, and deep endometriosis is now
called adenomyosis externa. Thus, there is a question as to whether adenomyosis is simply …

The pathophysiology of endometriosis and adenomyosis: tissue injury and repair

G Leyendecker, L Wildt, G Mall - Archives of gynecology and obstetrics, 2009 - Springer
Introduction This study presents a unifying concept of the pathophysiology of endometriosis
and adenomyosis. In particular, a physiological model is proposed that provides a …

Structure‐function relationships in tendons: a review

M Benjamin, E Kaiser, S Milz - Journal of anatomy, 2008 - Wiley Online Library
The purpose of the current review is to highlight the structure‐function relationship of
tendons and related structures to provide an overview for readers whose interest in tendons …

From mechanical loading to collagen synthesis, structural changes and function in human tendon

M Kjær, H Langberg, K Heinemeier… - … journal of medicine …, 2009 - Wiley Online Library
The adaptive response of connective tissue to loading requires increased synthesis and
turnover of matrix proteins, with special emphasis on collagen. Collagen formation and …

Soft robot–mediated autonomous adaptation to fibrotic capsule formation for improved drug delivery

R Beatty, KL Mendez, LHJ Schreiber, R Tarpey… - Science Robotics, 2023 - science.org
The foreign body response impedes the function and longevity of implantable drug delivery
devices. As a dense fibrotic capsule forms, integration of the device with the host tissue …

The role of mechanobiology in tendon healing

ML Killian, L Cavinatto, LM Galatz… - Journal of shoulder and …, 2012 - Elsevier
Mechanical cues affect tendon healing, homeostasis, and development in a variety of
settings. Alterations in the mechanical environment are known to result in changes in the …