Extracting morphological and sub-resolution features from optical coherence tomography images, a review with applications in cancer diagnosis

C Photiou, M Kassinopoulos, C Pitris - Photonics, 2023 - mdpi.com
Before they become invasive, early cancer cells exhibit specific and characteristic changes
that are routinely used by a histopathologist for diagnosis. Currently, these early …

Skin cancer margin detection using nanosensitive optical coherence tomography and a comparative study with confocal microscopy

R Dey, S Alexandrov, P Owens, J Kelly… - Biomedical Optics …, 2022 - opg.optica.org
Excision biopsy and histology represent the gold standard for morphological investigation of
the skin, in particular for cancer diagnostics. Nevertheless, a biopsy may alter the original …

Nanosensitive optical coherence tomography for detecting structural changes in stem cells

A Arangath, N Duffy, S Alexandrov, S James… - Biomedical Optics …, 2023 - opg.optica.org
Mesenchymal stromal cells (MSCs) are adult stem cells that have been widely investigated
for their potential to regenerate damaged and diseased tissues. Multiple pre-clinical studies …

Characterization of ultrastructural morphology in ex vivo bovine tissues using nanosensitive optical coherence tomography

P John, A Zam - Optics Communications, 2025 - Elsevier
The nanosensitive optical coherence tomography (nsOCT) technique was used to
characterize the ultrastructure of ex vivo bovine tissues. Intensity-based OCT images were …

Synthetic Fourier Domain Optical Coherence Tomography

S Alexandrov, R McAuley, R Dey… - Advanced Photonics …, 2024 - Wiley Online Library
A novel approach for image formation in optical coherence tomography (OCT) and
microscopy is presented. The depth resolution of OCT, including recently developed …

Simple characterization scheme for optical coherence tomography systems with application to a commercial and a near-isometric resolution fibre-based system

R Dey, Y Zhou, K Neuhaus, S Alexandrov… - IEEE Photonics …, 2021 - ieeexplore.ieee.org
Optical Coherence Tomography (OCT) is a rapidly growing imaging modality in biomedical
optics. OCT can perform high-resolution, cross-sectional imaging of the microstructure of …

Label free nano-sensitive optical imaging beyond resolution limit of the imaging system

S Alexandrov, R McAuley, R Dey… - 2024 24th International …, 2024 - ieeexplore.ieee.org
In this paper, we describe different approaches to improve resolution and get information
about structure beyond the resolution limit of the imaging system. The approaches are …

[PDF][PDF] High-resolution spectral domain optical coherence tomography system and structural characterization of ex vivo biological tissues using nanosensitive OCT

R Dey - 2023 - aran.library.nuigalway.ie
The most prevalent earlier medical imaging methods are X-ray radiography, ultrasound
imaging (ultrasonography), X-ray computed tomography (CT), and magnetic resonance …

Nanosensitive Optical Coherence Tomography for Tracking of Mesenchymal Stem Cells Labelled With Gold Nanostars

A Arangath, N Duffy, S Alexandrov, S James… - CLEO: Applications …, 2022 - opg.optica.org
Nanosensitive Optical Coherence Tomography for Tracking of Mesenchymal Stem Cells Labelled
With Gold Nanostars Page 1 Nanosensitive Optical Coherence Tomography for Tracking of …