Brain–Periphery Interactions in Huntington's Disease: Mediators and Lifestyle Interventions

J Burtscher, B Strasser, G Pepe, M Burtscher… - International Journal of …, 2024 - mdpi.com
Prominent pathological features of Huntington's disease (HD) are aggregations of mutated
Huntingtin protein (mHtt) in the brain and neurodegeneration, which causes characteristic …

NfL concentration in CSF is a quantitative marker of the rate of neurodegeneration in aging and Huntington's disease: a semi-mechanistic model-based analysis

M Machacek, E Garcia-Montoya, P McColgan… - Frontiers in …, 2024 - frontiersin.org
The concentrations of neurofilament light chain (NfL) in cerebrospinal fluid (CSF) and
plasma have become key biomarkers of many neurodegenerative diseases, including …

Modified rat pup cerebrospinal fluid collection method

J Wang, Z Dong, X Shi - Journal of Neuroscience Methods, 2024 - Elsevier
Background Cerebrospinal fluid (CSF) reflects biochemical changes in the brain due to its
direct contact with brain interstitial fluid, making it a valuable tool for diagnosing and …

Quantitative MRI to Investigate Central Nervous System Waste Clearance in Health and Neurodegenerative Disease

JJ Eisma - 2024 - ir.vanderbilt.edu
The choroid plexus comprises a highly vascularized collection of modified ependymal cells
functioning at the interface of the blood-cerebrospinal fluid (CSF) barrier. Within the stroma …