The altered activation or overexpression of protein kinases (PKs) is a major subject of
research in oncology and their inhibition using small molecules, protein kinases inhibitors …

Inflammation involves the activation of innate immune cells and is believed to play an
important role in the development and progression of both infectious and non-infectious …

We [1, 2] and others [3- 5] have been interested in designing and making new molecules
that have biological activities, medicinal uses, coordination behaviors [6- 8] and studying …

Abstract The reaction of 3-amino-5-phenylaminopyrazoles 2 with 3-(dimethylamino)
acrylonitrile derivatives resulted in a series of substituted pyrazolopyrimidine analogues 4 …

A general approach towards the synthesis of tetrahydro-4 H-pyrazolo [1, 5-a][1, 4] diazepin-4-
one, tetrahydro [1, 4] diazepino [1, 2-a] indol-1-one and tetrahydro-1 H-benzo [4, 5] imidazo …

The current work presents an objective overview of the impact of one important heterocyclic
structure, the pyrazole ring, in the development of anti-proliferative drugs. A set of 1551 …

Toxoplasmosis is an infectious disease with paramount impact worldwide, affecting many
vulnerable populations and representing a significant matter of concern. Current therapies …

Pyrazole and its derivatives are a pharmacologically and significantly active scaffolds that
have innumerable physiological and pharmacological activities. They can be very good …

A new family of six mononuclear indium (III) complexes of formula mer-[InIIICl3 (pz* H) 3]—
pz* H= pyrazole (pzH), or substituted pyrazoles: 4-Cl-pzH, 4-Br-pzH, 4-I-pzH, 4-Ph-pzH and …

A regioselective [3+ 2] cycloaddition (32CA) reaction to synthesize unsymmetric spiro-
barbituric pyrazolines containing a chromone or phenolic pyrazole moiety was achieved …