E-cadherin-mediated cell–cell adhesion is lost during the development of most epithelial
cancers. Recent evidence indicates that the loss of E-cadherin function, besides causing …

Vitamin D plays important, pleiotropic role in the maintenance of global homeostasis. Its
influence goes far beyond the regulation of calcium and phosphorus balance, as diverse …

Loss of expression of the intercellular adhesion molecule E‐cadherin frequently occurs in
invasive lobular breast carcinomas as a result of mutational inactivation. Expression patterns …

Sporadic aggressive fibromatosis (also called desmoid tumor) is a monoclonal proliferation
of spindle (fibrocyte-like) cells that is locally invasive but does not metastasize. A similarity to …

Publisher Summary This chapter discusses the methodological advantages and limitations
of the various approaches used to localize tumor suppressor genes on 3p, the short arm of …

Colorectal cancer is the fourth worldwide cause of death and even if some dietary habits are
consider risk factors, the contribution of food additives including foodgrade titanium dioxide …

The membranous, cytoplasmic and nuclear levels of beta-catenin were evaluated
immunohistochemically in archival tissue specimens from 96 Japanese patients with primary …

ABSTRACT The DF3/MUC1 mucin-like glycoprotein is highly overexpressed in human
carcinomas. Recent studies have demonstrated that the cytoplasmic domain of MUC1 …

The pathogenesis of gastric cancer is complex and related to multiple factors. Dysregulation
of intracellular signaling pathways represents a common pathogenic mechanism and may …

Animal models of colitis, which develop dysplasia and cancer similar to human ulcerative
colitis are needed to further investigate the dysplasia cancer sequence. This study describes …