Obesity and metabolic comorbidities: environmental diseases?
C Lubrano, G Genovesi, P Specchia… - Oxidative medicine …, 2013 - Wiley Online Library
Obesity and metabolic comorbidities represent increasing health problems. Endocrine
disrupting compounds (EDCs) are exogenous agents that change endocrine function and …
disrupting compounds (EDCs) are exogenous agents that change endocrine function and …
Risk assessment of occupational pesticide exposure: Use of endpoints and surrogates
SC Machado, I Martins - Regulatory Toxicology and Pharmacology, 2018 - Elsevier
Pesticides occupy a special position among various chemical agents that are present in the
environment because of to their toxicity, wide use, mainly in mixtures, and lack of action …
environment because of to their toxicity, wide use, mainly in mixtures, and lack of action …
[HTML][HTML] Increased levels of genotoxic damage in a Bolivian agricultural population exposed to mixtures of pesticides
During the past decades, farmers in low to middle-income countries have increased their
use of pesticides, and thereby the risk of being exposed to potentially genotoxic chemicals …
use of pesticides, and thereby the risk of being exposed to potentially genotoxic chemicals …
The Comet Assay as a Tool in Human Biomonitoring Studies of Environmental and Occupational Exposure to Chemicals—A Systematic Scoping Review
Biomonitoring of human populations exposed to chemical substances that can act as
potential mutagens or carcinogens, may enable the detection of damage and early disease …
potential mutagens or carcinogens, may enable the detection of damage and early disease …
Genetic polymorphisms of GSTM1, GSTT1 and GSTP1 and susceptibility to DNA damage in workers occupationally exposed to organophosphate pesticides
GSTM1, T1 and P1 are important enzymes of glutathione S-transferases (GSTs), involved in
the metabolism of many endogenous and exogenous compounds. Individual genetic …
the metabolism of many endogenous and exogenous compounds. Individual genetic …
Influence of CYP2C9, GSTM1, GSTT1 and NAT2 genetic polymorphisms on DNA damage in workers occupationally exposed to organophosphate pesticides
Previous studies have revealed that organophosphate pesticides (OPs) are primarily
metabolized by xenobiotic metabolizing enzymes (XMEs). Very few studies have explored …
metabolized by xenobiotic metabolizing enzymes (XMEs). Very few studies have explored …
Farmers exposed to pesticides have almost five times more DNA damage: a meta-analysis study
FA Nascimento, DM Silva, TMA Pedroso… - … Science and Pollution …, 2022 - Springer
We carried out a meta-analytical review of possible DNA damage resulting from
occupational exposure to pesticides in farmers in the scientific literature. After the search …
occupational exposure to pesticides in farmers in the scientific literature. After the search …
[HTML][HTML] Genetic polymorphisms and pesticide-induced DNA damage: a review
The drastic increase in pesticide applications makes human exposure inevitable either
through environment or occupation. Pesticide toxicity causes many adverse health effects …
through environment or occupation. Pesticide toxicity causes many adverse health effects …
Genotoxic and clastogenic activity of saponins extracted from Nauclea bark as assessed by the micronucleus and the comet assays in Chinese Hamster Ovary cells
ETHNOPHARMACOLOGICAL RELEVANCE: Bark extracts of Nauclea latifolia, Nauclea
diderrichii, Nauclea pobeguinii and Nauclea vandergutchii are used in traditional medicine …
diderrichii, Nauclea pobeguinii and Nauclea vandergutchii are used in traditional medicine …
The role of PON1 and CYP2D6 genes in susceptibility to organophosphorus chronic intoxication in Egyptian patients
AMT Khattab, AA Zayed, AI Ahmed, AG AbdelAal… - Neurotoxicology, 2016 - Elsevier
Abstract Background Paraoxonase-1 (PON1) activity toward organophosphorus (OP)
compounds shows inter-individual variations, rendering the identification of individuals' …
compounds shows inter-individual variations, rendering the identification of individuals' …