Introduction In order to assess the significance of drug levels measured in intensive care
medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is …

In order to assess the significance of drug levels measured in clinical and forensic toxicology
as well as for Therapeutic Drug Monitoring (TDM) it is essential that good collections of data …

Tramadol as a centrally acting analgesic is extensively used in the management of
moderate to severe pain. It slightly affects opioid receptors and inhibits the reuptake of …

Background: Eight analgesic preparations with approved indications for acute pain were
among the top 200 drugs prescribed in the United States in 2006. In addition, an estimated …

This study examines the relation between seizure and plasma tramadol concentration in
patients with tramadol poisoning, as a novel centrally acting analgesic used for the treatment …

Poisoning may also lead to both coma and multiple organ failure, also in youngsters without
a known major medical history. As not all toxic agents are routinely screened when a …

Tramadol is a centrally acting analgesic agent used in the treatment of mild to moderate
pain. It has a low affinity to opioid receptors and inhibits the reuptake of norepinephrin and …

Aims To describe alprazolam poisoning and the relative toxicity of alprazolam compared
with other benzodiazepines. Methods A database of consecutive poisoning admissions to a …

Background: We review recent findings on the toxicological interactions between alcohol
(ethanol) and benzodiazepines, and the combined use of benzodiazepines and alcohol in …

We described the findings of a study into the post-mortem redistribution (PMR) of 76 drugs
found in 129 drug-related cases between 2006 and 2009. Seventy six drugs (psychotropic …