High-resolution native mass spectrometry

S Tamara, MA den Boer, AJR Heck - Chemical Reviews, 2021 - ACS Publications
Native mass spectrometry (MS) involves the analysis and characterization of
macromolecules, predominantly intact proteins and protein complexes, whereby as much as …

[HTML][HTML] High-resolution mass spectrometry (HRMS) methods for nontarget discovery and characterization of poly-and per-fluoroalkyl substances (PFASs) in …

Y Liu, LA D'Agostino, G Qu, G Jiang… - TrAC Trends in Analytical …, 2019 - Elsevier
Widespread environmental contamination of legacy long-chain poly-and per-fluoroalkyl
substances (PFASs) has triggered chemical regulatory action and a global transitioning to …

[HTML][HTML] Ion mobility-mass spectrometry: time-dispersive instrumentation

JC May, JA McLean - Analytical chemistry, 2015 - ACS Publications
The field of ion mobility-mass spectrometry (IM-MS) has grown with significant momentum in
recent years in both fundamental advances and pioneering applications. A search of the …

Data processing, multi-omic pathway mapping, and metabolite activity analysis using XCMS Online

EM Forsberg, T Huan, D Rinehart, HP Benton… - Nature protocols, 2018 - nature.com
Abstract Systems biology is the study of complex living organisms, and as such, analysis on
a systems-wide scale involves the collection of information-dense data sets that are …

21 Tesla Fourier transform ion cyclotron resonance mass spectrometer: a national resource for ultrahigh resolution mass analysis

CL Hendrickson, JP Quinn, NK Kaiser… - Journal of the …, 2015 - ACS Publications
We describe the design and initial performance of the first 21 tesla Fourier transform ion
cyclotron resonance (FT-ICR) mass spectrometer. The 21 tesla magnet is the highest field …

High-throughput proteomics

Z Zhang, S Wu, DL Stenoien… - Annual review of …, 2014 - annualreviews.org
Mass spectrometry (MS)–based high-throughput proteomics is the core technique for large-
scale protein characterization. Due to the extreme complexity of proteomes, sophisticated …

[HTML][HTML] Quadrupole time-of-flight mass spectrometry: a paradigm shift in toxicology screening applications

DR Allen, BC McWhinney - The Clinical Biochemist Reviews, 2019 - ncbi.nlm.nih.gov
The screening of biological samples for the presence of illicit or legal substances is an
important frontline tool in both clinical and forensic toxicology. In the clinical setting, drug …

Chemical modification of amino acids by atmospheric-pressure cold plasma in aqueous solution

E Takai, T Kitamura, J Kuwabara, S Ikawa… - Journal of Physics D …, 2014 - iopscience.iop.org
Plasma medicine is an attractive new research area, but the principles of plasma
modification of biomolecules in aqueous solution remain elusive. In this study, we …

High-throughput discovery metabolomics

T Fuhrer, N Zamboni - Current opinion in biotechnology, 2015 - Elsevier
Highlights•Chromatography-based mass spectrometry (MS) allows profiling 100 samples
per day.•Thousands of samples per day can be efficiently analyzed by omitting …

Developments in FT‐ICR MS instrumentation, ionization techniques, and data interpretation methods for petroleomics

Y Cho, A Ahmed, A Islam, S Kim - Mass spectrometry reviews, 2015 - Wiley Online Library
Because of the increasing importance of heavy and unconventional crude oil as an energy
source, there is a growing need for petroleomics: the pursuit of more complete and detailed …