Cytokines are critical in regulating immune responses and cellular behavior, playing dual
roles in both normal physiology and the pathology of diseases such as cancer. These …

IL-1 belongs to a family of 11 members and is one of the seven receptor-agonists with pro-
inflammatory activity. Beyond its biological role as a regulator of the innate immune …

Primary graft dysfunction (PGD) is the predominant cause of early graft loss following lung
transplantation. We recently demonstrated that donor pulmonary intravascular nonclassical …

Tumor-suppressive effects of resveratrol have been shown in various types of cancer.
However, regulation of tumor microenvironment by resveratrol is still unclear. Recent …

The review focuses on mechanistic evidence for the link between obesity and breast cancer.
According to the IARC study, there is sufficient evidence that obesity is closely related to a …

Cancer is a category of diseases involving abnormal cell growth with the potential to invade
other parts of the body. Chemotherapy is the most widely used first-line treatment for multiple …

Our understanding of cancer and the key pathways that drive cancer survival has expanded
rapidly over the past several decades. However, there are still important challenges that …

Breast cancer is one of the leading causes of cancer-related deaths in women worldwide. It
is a cancer that originates from the mammary ducts and involves mutations in multiple …

Inflammation is a critical component of cancer development. Previously, we showed in vitro
that IL-1β treatment of non-invasive human breast cancer MCF-7 cells promoted their …

Lymphovascular invasion (LVI) is associated with poor outcome in breast cancer (BC);
however, its underlying mechanisms remain ill-defined. LVI in BC develops through complex …