The authors provide a comprehensive summary of all randomized, controlled trials (n= 76)
involving the clinical administration of liposomal bupivacaine (Exparel; Pacira …

BACKGROUND Pain after cardiac surgery via median sternotomy can be difficult to treat,
and if inadequately managed can lead to respiratory complications, prolonged hospital stays …

Importance The use of intercostal nerve block (ICNB) analgesia with local anesthesia is
common in thoracic surgery. However, the benefits and safety of ICNB among adult patients …

Objective: To explore the effect of pecto-intercostal fascial plane block (PIFB) on
postoperative opioid requirements, pain scores, lengths of intensive care unit and hospital …

The remarkable number of new molecular entities approved per year as parenteral drugs,
such as biologics and complex active pharmaceutical ingredients, calls for innovative and …

Ultrasound guided parasternal block is a regional anaesthesia technique targeting the
anterior branches of intercostal nerves, which supply the anterior thoracic wall. The aim of …

The statements and recommendations contained in this report are primarily based on the
available literature and expert consensus. Decisions should be individualized and tailored …

Abstract Purpose of Review Multimodal pain management is the most effective way to treat
postsurgical pain. However, the use of opioids for acute pain management has unfortunately …

Objectives: We aimed to evaluate the analgesic efficacy of ultrasound-guided bilateral
pectointercostal fascial plane block after open heart surgeries. Methods: Seventy patients …

Background Patients usually suffer acute pain after cardiac surgery. Numerous regional
anesthetic techniques have been used for those patients under general anesthesia. The …