The intestinal epithelial tight junction (TJ) barrier controls the paracellular permeation of
contents from the intestinal lumen into the intestinal tissue and systemic circulation. A …

The importance of maintaining contractile function in aortic smooth muscle cells (SMCs) is
evident by the fact that heterozygous mutations in the major structural proteins or kinases …

The endoplasmic reticulum (ER) and mitochondria are physically connected to form
dedicated structural domains known as mitochondria-associated ER membranes (MAMs) …

Polyglutamylation is a posttranslational modification that generates glutamate side chains
on tubulins and other proteins. Although this modification has been shown to be reversible …

Mutations in smooth muscle cell (SMC)-specific isoforms of α-actin and β-myosin heavy
chain, two major components of the SMC contractile unit, cause familial thoracic aortic …

Microvascular barrier dysfunction is implicated in the initiation and progression of
inflammation, posttraumatic complications, sepsis, ischaemia–reperfusion injury …

The intestinal epithelial apical junctional complex, which includes tight and adherens
junctions, contributes to the intestinal barrier function via their role in regulating paracellular …

Repetitive, calcium-mediated contractile activity renders cardiomyocytes critically dependent
on a sustained energy supply and adequate calcium buffering, both of which are provided …

Smooth muscle cell (SMC) differentiation is an essential component of vascular
development and these cells perform biosynthetic, proliferative, and contractile roles in the …

• Introduction• Mechanisms that regulate LC20 phosphorylation‐Regulation of myosin
phosphatase‐CaMKII• Mechanisms that regulate the access of myosin to actin‐Caldesmon …