Oral cancer is a type of cancer that develops in the mouth and is one of the deadliest
malignancies in the world. Currently surgical, radiation therapy, and chemotherapy are most …

Heterogeneity describes the differences among cancer cells within and between tumors. It
refers to cancer cells describing variations in morphology, transcriptional profiles …

Despite the promise of immune checkpoint inhibition (ICI), therapeutic responses remain
limited. This raises the possibility that standard of care treatments delivered in concert may …

Microneedle arrays (MNAs) are small patches containing hundreds of short projections that
deliver signals directly to dermal layers without causing pain. These technologies are of …

Oral cavity carcinomas are the most frequent malignancies among head and neck
malignancies. Oral tumors include not only oral cancer cells with different potency and …

Preclinical models of cancer have long been paramount to understanding tumor
development and advancing the treatment of cancer. Creating preclinical models that mimic …

Cancer patients treated with immune checkpoint inhibitors (ICIs) are susceptible to a broad
and variable array of immune‐related adverse events (irAEs). With increasing clinical use of …

Background Nano-sized drug delivery system has been widely studied as a potential
technique to promote tumor-specific delivery of anticancer drugs due to its passive targeting …

Cancer constitutes a significant threat to patients' lives worldwide. Immunotherapy,
particularly immune checkpoint inhibitors (ICIs) that boost antitumor immunity by targeting …

Superficial tumors are still challenging to overcome due to the high risk and toxicity of
surgery and conventional chemotherapy. Microneedles (MNs) are widely used in the …