The annual incidence of venous thrombosis, one of the leading causes of mortality and
morbidity, increases from 1 per 100,000 during childhood to 1 per 100 in old age. 1 In this …

BACKGROUND: The association between the inherited gene mutations of factor V,
prothrombin, and homocysteine metabolism and venous thromboembolic events is accepted …

Stroke ranks as the third leading cause of death in the United States. It is now estimated that
there are more than 700000 incident strokes annually and 4.4 million stroke survivors. 1, 2 …

Abstract The factor II G20210A mutation is a recently identified congenital risk factor for
venous thrombosis. Its role in artery disease is still undefined. We investigated 72 patients …

Background—Hypercoagulable states are a recognized, albeit uncommon, etiology of
ischemic stroke. It is unclear how often the results of specialized coagulation tests affect …

Platelet membrane glycoprotein Ib(GPIb) is a major receptor for von Willebrand factor
and thrombin, which plays a key role in the initial development of thrombi. Two …

A sequence variation in the 3′‐untranslated region of the prothrombin (PT) gene (20210
G→ A) was recently claimed to be associated with elevated plasma prothrombin levels and …

The pathogenesis of arterial thrombotic disease involves multiple genetic and environmental
factors related to atherosclerosis and thrombosis. Acute thrombosis at the site of a ruptured …

We investigated the prevalence of the new recently reported mutation in the prothrombin
gene (20210 A) in a sample of 116 unrelated patients with venous thromboembolism. We …

Arterial and venous thromboses, with their clinical manifestations such as stroke, myocardial
infarction (MI), or pulmonary embolism, are the major causes of death in developed …