Telomeres are nucleoprotein caps flanking DNA. They are shortened by cell division and
oxidative stress and are lengthened by the enzyme telomerase and DNA exchange during …

Telomeres, the DNA–protein structures located at the ends of chromosomes, have been
proposed to act as a biomarker of aging. In this review, the human evidence that telomere …

Background The epigenetic clock, in particular epigenetic pre-aging quantified by the so-
called DNA methylation age acceleration, has recently been suggested to closely correlate …

Telomeres are the protective end caps of chromosomes and shorten with every cell division.
Telomere length has been proposed as a biomarker of biological age and a risk factor for …

Telomeres are at the non-coding ends of linear chromosomes. Through a complex 3-
dimensional structure, they protect the coding DNA and ensure appropriate separation of …

Telomere length (TL) is emerging as a biomarker for aging and survival. To evaluate factors
influencing this trait, we measured TL in a large homogeneous population, estimated the …

Evidence assembled over the last decade shows that average telomere length (TL) acts as a
biomarker for biological aging and cardiovascular disease (CVD) in particular. Although …

Although telomere length (TL) is known to play a critical role in cellular senescence, the
relationship of TL to aging and longevity in humans is not well understood. In a large biracial …

Although evidence supports the function of telomere length (TL) as a marker for biological
aging, no major determinants of TL are known besides inheritance, age and gender. Here …

Telomeres are protein-DNA complexes localized at the ends of linear chromosomes
constituted by short, tandem G-rich hexanucleotide repeats and associated proteins. Their …