Inflammation occurs in the vasculature as a response to injury, lipid peroxidation, and
perhaps infection. Various risk factors, including hypertension, diabetes, and smoking, are …

Ample evidence exists in support of the potent anti-inflammatory properties of statins. In cell
studies and animal models statins exert beneficial cardiovascular effects. By inhibiting …

The HMG Co-enzyme inhibitors and new lipid-modifying agents expand their new
therapeutic target options in the field of medical profession. Statins have been described as …

Progress in the diagnosis, treatment, and prevention of atherosclerotic coronary artery
disease is dependent on a greater understanding of the mechanisms of coronary plaque …

Chronic inflammation enhances the detrimental role of dyslipidaemia during atherogenesis.
Statins are among the most effective anti-atherosclerotic medications, being able to impact …

OBJECTIVE: Plaque with dense inflammatory cells, including macrophages, thin fibrous cap
and superficial necrotic/lipid core is thought to be prone-to-rupture. We report a time …

The current OCT catheter has a stationary outer sheath so that the inner imaging core can
rotate safely to provide crosssectional images. This design also facilitates an automated …

Up to two-thirds of acute myocardial infarctions develop at sites of culprit lesions without a
significant stenosis. New imaging techniques are needed to identify those lesions with an …

We review fluorescence lifetime techniques including time-resolved laser-induced
fluorescence spectroscopy (TR-LIFS) and fluorescence lifetime imaging microscopy (FLIM) …

Since publication of the First Edition, advances in the diagnosis and prevention and
treatment strategies of the vulnerable plaque have necessitated this greatly expanded …