Alkaloids for cancer prevention and therapy: Current progress and future perspectives

A Mondal, A Gandhi, C Fimognari, AG Atanasov… - European journal of …, 2019 - Elsevier
Alkaloids are important chemical compounds that serve as a rich source for drug discovery.
Numerous alkaloids screened from medicinal plants and herbs showed antiproliferative and …

The signaling pathways and targets of traditional Chinese medicine and natural medicine in triple-negative breast cancer

Z Yang, Q Zhang, L Yu, J Zhu, Y Cao, X Gao - Journal of …, 2021 - Elsevier
Ethnopharmacological relevance Triple-negative breast cancer (TNBC) has a poorer
prognosis than other subtypes due to its strong invasion and higher risk of distant …

[HTML][HTML] Discovery of piperlongumine as a potential novel lead for the development of senolytic agents

Y Wang, J Chang, X Liu, X Zhang, S Zhang… - Aging (Albany …, 2016 - ncbi.nlm.nih.gov
Accumulating evidence indicates that senescent cells play an important role in many age-
associated diseases. The pharmacological depletion of senescent cells (SCs) with a …

Recent advances in phytochemical based nano-drug delivery systems to combat breast cancer: A review

R Solanki, B Jodha, KE Prabina, N Aggarwal… - Journal of Drug Delivery …, 2022 - Elsevier
Breast Cancer is the most common cancer in women worldwide. Recently bioactive plant
products, namely phytochemicals are being been explored by researchers for their …

Therapeutic progress and challenges for triple negative breast cancer: Targeted therapy and immunotherapy

R Yang, Y Li, H Wang, T Qin, X Yin, X Ma - Molecular biomedicine, 2022 - Springer
Triple negative breast cancer (TNBC) is a subtype of breast cancer, with estrogen receptor,
human epidermal growth factor receptor 2 and progesterone receptor negative. TNBC is …

Role of Medicinal plant‐derived Nutraceuticals as a potential target for the treatment of breast cancer

KS Alharbi, WH Almalki, HA Makeen… - Journal of Food …, 2022 - Wiley Online Library
Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many
cancer‐related deaths. Over some years, chemotherapy, hormone treatment, radiation, and …

Promoting apoptosis, a promising way to treat breast cancer with natural products: A comprehensive review

L Yuan, Y Cai, L Zhang, S Liu, P Li, X Li - Frontiers in pharmacology, 2022 - frontiersin.org
Breast cancer is one of the top-ranked malignant carcinomas associated with morbidity and
mortality in women worldwide. Chemotherapy is one of the main approaches to breast …

Recent advances with precision medicine treatment for breast cancer including triple-negative sub-type

MA Subhan, F Parveen, H Shah, SSK Yalamarty… - Cancers, 2023 - mdpi.com
Simple Summary The progress of next-generation sequencing technologies has raised
huge expectations for precision-medicine therapy approaches in breast cancer and triple …

Piperlongumine, a potent anticancer phytotherapeutic: Perspectives on contemporary status and future possibilities as an anticancer agent

SK Tripathi, BK Biswal - Pharmacological Research, 2020 - Elsevier
Piperlongumine, a white to beige biologically active alkaloid/amide phytochemical, has high
pharmacological relevance as an anticancer agent. Piperlongumine has several biological …

Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review

S Fakhri, SZ Moradi, MH Farzaei, A Bishayee - Seminars in cancer biology, 2022 - Elsevier
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …