Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists
J Younkin, SA Gaitonde, A Ellaithy… - ACS chemical …, 2016 - ACS Publications
Several pharmacophore models have been proposed for 5-HT2A serotonin receptor
antagonists. These typically consist of two aromatic/hydrophobic moieties separated by a …
antagonists. These typically consist of two aromatic/hydrophobic moieties separated by a …
Antipsicóticos atípicos versus efeito obesogênico sob a óptica da química medicinal
AP Schmitz, OC Kreutz, ES Suyenaga - Revista Eletrônica de …, 2015 - revistas.ufg.br
Os fármacos antipsicóticos são os principais agentes utilizados no tratamento da
esquizofrenia e atuam principalmente como antagonistas do receptor dopaminérgico D2 …
esquizofrenia e atuam principalmente como antagonistas do receptor dopaminérgico D2 …
Pharmacophore and molecular docking based identification of novel structurally diverse PDE-5 inhibitors
S Paliwal, A Mittal, M Sharma, A Pandey… - Medicinal Chemistry …, 2015 - Springer
In view that PDE5 is a potential target for the design of antihypertensive drugs a
pharmacophore and molecular docking based virtual screening protocol was implemented …
pharmacophore and molecular docking based virtual screening protocol was implemented …
Molecular dynamics simulated validation of anti-cancerous alkaloids as Topo IIβ inhibitors screened by QSAR, pharmacophore and molecular docking approaches
S Singh, M Awasthi, VP Pandey, B Pandey… - Medicinal Chemistry …, 2015 - Springer
Looking to the recent roles of topoisomerases in various types of cancers, in the present
paper, a quantitative structure–activity relationship model, based on genetic function …
paper, a quantitative structure–activity relationship model, based on genetic function …
[PDF][PDF] Ligand and Structure-Based Pharmacophore Modelling, Computer-aided Screening and Molecular Docking to Detect Novel NS5B Polymerase Inhibitors as …
A Derashri, A Dwivedi, M Maan, DD Bhandari - 2022 - biointerfaceresearch.com
The ongoing interest of researchers in the direct-acting NS5B inhibitors in the development
of viral disease hepatitis has attracted our attention in the direction of the development of a …
of viral disease hepatitis has attracted our attention in the direction of the development of a …
PHARMACOPHORIC EVALUATION OF 5-HT2A AND 5-HT2B SEROTONIN RECPEPTORS
P Hemanth - 2021 - scholarscompass.vcu.edu
Abstract Serotonin (5-HT) receptors represent a class of receptors involved in a variety of
physiological processes including regulation of mood, perception, cognition, appetite, and …
physiological processes including regulation of mood, perception, cognition, appetite, and …
[图书][B] A Roadmap for Development of Novel Antipsychotic Agents Based on a Risperidone Scaffold
UH Shah - 2017 - search.proquest.com
Schizophrenia is a chronic psychotic illness affecting~ 21 million people globally. Currently
available antipsychotic agents act through a dopamine D 2 receptor mechanism, and …
available antipsychotic agents act through a dopamine D 2 receptor mechanism, and …
ANTIPSICÓTICOS ATÍPICOS VERSUS EFEITO OBESOGÊNICO SOB A ÓPTICA DA QUĺMICA FARMACÊUTICA.
AP Schmitz, OC Kreutz… - Electronic Journal of …, 2015 - search.ebscohost.com
Os fármacos antipsicóticos são os principais agentes utilizados no tratamento da
esquizofrenia e atuam principalmente como antagonistas do receptor dopaminérgico D2 …
esquizofrenia e atuam principalmente como antagonistas do receptor dopaminérgico D2 …