Dose-response for assessing the cancer risk of inorganic arsenic in drinking water: the scientific basis for use of a threshold approach

JS Tsuji, ET Chang, PR Gentry, HJ Clewell… - Critical reviews in …, 2019 - Taylor & Francis
The biologic effects of inorganic arsenic predominantly involve reaction of the trivalent forms
with sulfhydryl groups in critical proteins in target cells, potentially leading to various …

[HTML][HTML] 'Omics in environmental epidemiological studies of chemical exposures: a systematic evidence map

S Kim, H Hollinger, EG Radke - Environment International, 2022 - Elsevier
Background Systematic evidence maps are increasingly used to develop chemical risk
assessments. These maps can provide an overview of available studies and relevant study …

Highly sensitive and selective detection of arsenic using electrogenerated nanotextured gold assemblage

NUA Babar, KS Joya, MA Tayyab, MN Ashiq… - ACS …, 2019 - ACS Publications
Arsenic is considered as a toxic heavy metal which is highly detrimental to ecological
systems, and long-term exposure to it is highly dangerous to life as it can cause serious …

[HTML][HTML] Mixtures modeling identifies chemical inducers versus repressors of toxicity associated with wildfire smoke

JE Rager, J Clark, LA Eaves, V Avula… - Science of the Total …, 2021 - Elsevier
Exposure to wildfire smoke continues to be a growing threat to public health, yet the
chemical components in wildfire smoke that primarily drive toxicity and associated disease …

A network of sputum microRNAs is associated with neutrophilic airway inflammation in asthma

JL Gomez, A Chen, MP Diaz, N Zirn… - American journal of …, 2020 - atsjournals.org
Rationale: MicroRNAs are potent regulators of biologic systems that are critical to tissue
homeostasis. Individual microRNAs have been identified in airway samples. However, a …

[HTML][HTML] Predictive modeling of biological responses in the rat liver using in vitro Tox21 bioactivity: Benefits from high-throughput toxicokinetics

C Ring, NS Sipes, JH Hsieh, C Carberry… - Computational …, 2021 - Elsevier
Computational methods are needed to more efficiently leverage data from in vitro cell-based
models to predict what occurs within whole body systems after chemical insults. This study …

The placenta epigenome–brain axis: placental epigenomic and transcriptomic responses that preprogram cognitive impairment

AN Freedman, LA Eaves, JE Rager… - …, 2022 - Taylor & Francis
Aim: The placenta–brain axis reflects a developmental linkage where disrupted placental
function is associated with impaired neurodevelopment later in life. Placental gene …

Goethite (α-FeOOH) nanoparticles wrapped on reduced graphene oxide nanosheet for sensitive electrochemical detection of arsenic (III)

V Vinoth, K Shanmugaraj, N Pugazhenthiran… - Ceramics …, 2024 - Elsevier
The goethite (α-FeOOH) nanoparticles were wrapped on the reduced graphene oxide (rGO)
to synthesize the α-FeOOH/rGO nanocomposites. The nanocomposites (NCs) were initially …

[HTML][HTML] Integrative exposomic, transcriptomic, epigenomic analyses of human placental samples links understudied chemicals to preeclampsia

A Chao, J Grossman, C Carberry, Y Lai… - Environment …, 2022 - Elsevier
Background Environmental health research has recently undergone a dramatic shift, with
ongoing technological advancements allowing for broader coverage of exposure and …

Wildfire variable toxicity: Identifying biomass smoke exposure groupings through transcriptomic similarity scoring

LE Koval, CK Carberry, YH Kim… - … science & technology, 2022 - ACS Publications
The prevalence of wildfires continues to grow globally with exposures resulting in increased
disease risk. Characterizing these health risks remains difficult due to the wide landscape of …