AI-powered therapeutic target discovery

FW Pun, IV Ozerov, A Zhavoronkov - Trends in pharmacological sciences, 2023 - cell.com
Disease modeling and target identification are the most crucial initial steps in drug
discovery, and influence the probability of success at every step of drug development …

Synthetic data generation: State of the art in health care domain

H Murtaza, M Ahmed, NF Khan, G Murtaza… - Computer Science …, 2023 - Elsevier
Recent progress in artificial intelligence and machine learning has led to the growth of
research in every aspect of life including the health care domain. However, privacy risks and …

Current strategies to address data scarcity in artificial intelligence-based drug discovery: A comprehensive review

A Gangwal, A Ansari, I Ahmad, AK Azad… - Computers in Biology …, 2024 - Elsevier
Artificial intelligence (AI) has played a vital role in computer-aided drug design (CADD). This
development has been further accelerated with the increasing use of machine learning (ML) …

Synthetic data as an enabler for machine learning applications in medicine

JF Rajotte, R Bergen, DL Buckeridge, K El Emam, R Ng… - Iscience, 2022 - cell.com
Synthetic data generation is the process of using machine learning methods to train a model
that captures the patterns in a real dataset. Then new or synthetic data can be generated …

Synthetic data generation by artificial intelligence to accelerate research and precision medicine in hematology

S D'amico, D Dall'Olio, C Sala, L Dall'Olio… - JCO Clinical Cancer …, 2023 - ascopubs.org
PURPOSE Synthetic data are artificial data generated without including any real patient
information by an algorithm trained to learn the characteristics of a real source data set and …

A survey of generative adversarial networks for synthesizing structured electronic health records

GO Ghosheh, J Li, T Zhu - ACM Computing Surveys, 2024 - dl.acm.org
Electronic Health Records (EHRs) are a valuable asset to facilitate clinical research and
point of care applications; however, many challenges such as data privacy concerns impede …

Validating a membership disclosure metric for synthetic health data

K El Emam, L Mosquera, X Fang - JAMIA open, 2022 - academic.oup.com
Background One of the increasingly accepted methods to evaluate the privacy of synthetic
data is by measuring the risk of membership disclosure. This is a measure of the F1 …

Systematic review of generative modelling tools and utility metrics for fully synthetic tabular data

AD Lautrup, T Hyrup, A Zimek… - ACM Computing …, 2024 - dl.acm.org
Sharing data with third parties is essential for advancing science, but it is becoming more
and more difficult with the rise of data protection regulations, ethical restrictions, and growing …

Syntheval: a framework for detailed utility and privacy evaluation of tabular synthetic data

AD Lautrup, T Hyrup, A Zimek… - Data Mining and …, 2025 - Springer
With the growing demand for synthetic data to address contemporary issues in machine
learning, such as data scarcity, data fairness, and data privacy, having robust tools for …

A method for generating synthetic longitudinal health data

L Mosquera, K El Emam, L Ding, V Sharma… - BMC Medical Research …, 2023 - Springer
Getting access to administrative health data for research purposes is a difficult and time-
consuming process due to increasingly demanding privacy regulations. An alternative …