Using chitosan, hyaluronic acid, alginate, and gelatin-based smart biological hydrogels for drug delivery in oral mucosal lesions: A review

N Samiraninezhad, K Asadi, H Rezazadeh… - International Journal of …, 2023 - Elsevier
Aims Oral mucosal diseases can lead to pain, difficulty speaking and eating, psychological
distress, and cancer. Topical drug delivery using biological macromolecules, specifically …

Advancements in the pharmaceutical applications of probiotics: Dosage forms and formulation technology

KC Baral, R Bajracharya, SH Lee… - International journal of …, 2021 - Taylor & Francis
Probiotics have demonstrated their high potential to treat and/or prevent various diseases
including neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory …

Mucoadhesion and mechanical assessment of oral films

S Alaei, H Omidian - European Journal of Pharmaceutical Sciences, 2021 - Elsevier
Aligned with efforts to overcome shortcomings of conventional oral dosage forms,
mucoadhesive oral thin films have been the focus of drug development. Transmucosal drug …

Role of probiotics in managing various human diseases, from oral pathology to cancer and gastrointestinal diseases

OA Petrariu, IC Barbu, AG Niculescu… - Frontiers in …, 2024 - frontiersin.org
The imbalance of microbial composition and diversity in favor of pathogenic microorganisms
combined with a loss of beneficial gut microbiota taxa results from factors such as age, diet …

Challenges in Optimizing Nanoplatforms Used for Local and Systemic Delivery in the Oral Cavity

DI Cocoș, O Dumitriu Buzia, AL Tatu, M Dinu… - Pharmaceutics, 2024 - mdpi.com
In this study, we focused on innovative approaches to improve drug administration in oral
pathology, especially by transmucosal and transdermal pathways. These improvements …

The dawning era of oral thin films for nutraceutical delivery: From laboratory to clinic

N Khan, SS Dogra, A Saneja - Biotechnology Advances, 2024 - Elsevier
Oral thin films (OTFs) are innovative dosage forms that have gained tremendous attention for
the delivery of nutraceuticals. They are ultra-thin, flexible sheets that can be easily placed on …

Polysaccharide-based drug delivery systems for the treatment of periodontitis

N Baranov, M Popa, LI Atanase, DL Ichim - Molecules, 2021 - mdpi.com
Periodontal diseases are worldwide health problems that negatively affect the lifestyle of
many people. The long-term effect of the classical treatments, including the mechanical …

[HTML][HTML] The use of natural gums to produce nano-based hydrogels and films for topical application

MHM Sari, LM Ferreira, L Cruz - International Journal of Pharmaceutics, 2022 - Elsevier
Natural gums are a source of biopolymeric materials with a wide range of applications for
multiple purposes. These polysaccharides are extensively explored due to their low toxicity …

Implications of oral dysbiosis and HPV infection in head and neck cancer: from molecular and cellular mechanisms to early diagnosis and therapy

M Constantin, MC Chifiriuc, G Mihaescu… - Frontiers in …, 2023 - frontiersin.org
Head and neck cancer (HNC) is the sixth most common type of cancer, with more than half a
million new cases annually. This review focuses on the role of oral dysbiosis and HPV …

Bilayer mucoadhesive buccal film for mucosal ulcers treatment: Development, characterization, and single study case

TFR Alves, AC Rios, K da Silva Pontes, DL Portella… - Pharmaceutics, 2020 - mdpi.com
The formation of mucosal ulcers is an end result of epithelial damage, and it occurs due to
some specific causes, such as trauma, aphthous stomatitis, lichen planus and lichenoid …