Advances in platelet function testing—light transmission aggregometry and beyond

J Le Blanc, F Mullier, C Vayne… - Journal of clinical …, 2020 - mdpi.com
Platelet function testing is essential for the diagnosis of hemostasis disorders. While there
are many methods used to test platelet function for research purposes, standardization is …

Platelet function testing: update and future directions

JB Larsen, AM Hvas, JA Hojbjerg - Seminars in Thrombosis …, 2023 - thieme-connect.com
Platelets play a key role in maintaining normal hemostasis and are also recognized as
partners in the development of arterial thrombosis. Today, platelet function testing is used for …

Update on diagnostic testing for platelet function disorders: What is practical and useful?

CPM Hayward, KA Moffat, J Brunet… - … journal of laboratory …, 2019 - Wiley Online Library
Introduction Platelet function disorders (PFD) are an important group of bleeding disorders
that require validated and practical laboratory strategies for diagnosis. Methods This review …

Harmonizing light transmission aggregometry in the Netherlands by implementation of the SSC-ISTH guideline

ICA Munnix, R Van Oerle, P Verhezen, P Kuijper… - Platelets, 2021 - Taylor & Francis
Light transmission aggregometry (LTA) is considered the gold standard method for
evaluation of platelet function. However, there are a lot of variation in protocols (pre …

Classic light transmission platelet aggregometry: Do we still need it?

J Gebetsberger, F Prüller - Hämostaseologie, 2024 - thieme-connect.com
For more than 50 years, light transmission aggregometry has been accepted as the gold
standard test for diagnosing inherited platelet disorders in platelet-rich plasma, although …

The current role of platelet function testing in clinical practice

GA Mason, DJ Rabbolini - Seminars in Thrombosis and …, 2021 - thieme-connect.com
Platelet dysfunction, whether hereditary or acquired, may increase an individual's risk of
spontaneous, posttraumatic, or postoperative bleeding. Conversely, increased platelet …

Evaluation of an automated platelet aggregation method for detection of congenital or acquired platelet function defects: Automated aggregometry for detecting …

A Lecchi, M Capecchi, L Padovan, A Artoni… - Blood …, 2023 - bloodtransfusion.it
Background-Light transmission aggregometry (LTA) is the most widely used laboratory
method for an initial screening of patients with a suspected platelet function defect (PFD) …

[HTML][HTML] The Diagnostic Assessment of Platelet Function Defects

K Althaus, G Hoepner, B Zieger, F Prüller… - …, 2025 - thieme-connect.com
Congenital platelet disorders are rare and targeted treatment is usually not possible.
Inherited platelet function disorders (iPFDs) can affect surface receptors and multiple platelet …

Comparison of the effect of Morphine and Fentanyl in patients with acute coronary syndrome receiving Ticagrelor-The COMET (Comparison Morphine, Fentanyl and …

NB Senguttuvan, F Suman, TA Paneerselvam… - International Journal of …, 2021 - Elsevier
Introduction Dual antiplatelet therapy (DAPT) remains the cornerstone of acute coronary
syndrome (ACS) management, and ticagrelor is one of the commonly used second …

Correlation between the VerifyNow P2Y12 assay and the newly developed APAL system in neuroendovascular patients

K Uematsu, T Sakayori, H Ishida… - Annals of Clinical & …, 2020 - Assoc Clin Scientists
Objective Light transmission aggregometry (LTA) is the gold standard method for assessing
platelet function. Recently, a new parameter called adenosine diphosphate (ADP)-induced …