Neuropilins (NRPs) are non-tyrosine kinase cell surface glycoproteins expressed in all
vertebrates and widely conserved across species. The two isoforms, such as neuropilin-1 …

Prostate cancer (PCa) accounts for a high number of deaths in males with no available
curative treatments. Patients with PCa are commonly diagnosed in advanced stages due to …

Fatty acid β-oxidation (FAO) is the main bioenergetic pathway in human prostate cancer
(PCa) and a promising novel therapeutic vulnerability. Here we demonstrate therapeutic …

Cancer metastasis is a malignant process by which tumor cells migrate from their primary
site of origin to other organs. It is the main cause of poor prognosis in cancer patients …

Prostate cancer (PCa) is the most common malignant tumor with a high global incidence in
males. The mechanism underlying PCa progression is still not clear. This study observed …

Neuropilin-1 and Neuropilin-2 form a small family of plasma membrane spanning receptors
originally identified by the binding of semaphorin and vascular endothelial growth factor …

Myeloid checkpoints are receptors on the myeloid cell surface which can mediate inhibitory
signals to modulate anti-tumor immune activities. They can either inhibit cellular …

African ancestry is a significant risk factor for prostate cancer and advanced disease. Yet,
genetic studies have largely been conducted outside the context of Sub-Saharan Africa …

Neuropilin 1 (NRP1) represents one of the two homologous neuropilins (NRP, splice
variants of neuropilin 2 are the other) found in all vertebrates. It forms a transmembrane …

Background Neuroendocrine prostate cancer (NEPC) is a multi-resistant variant of prostate
cancer (PCa) that has become a major challenge in clinics. Understanding the …