A large body of evidence indicates the existence of a complex pathophysiological
relationship between cardiovascular diseases and cancer. Mitochondria are crucial …

The skin is the largest organ of the human body and the first line of defense against
environmental hazards. Many factors, including internal factors such as natural aging and …

There remains an unmet need to identify novel therapeutic strategies capable of protecting
the myocardium against the detrimental effects of acute ischemia–reperfusion injury (IRI), to …

Ferroptosis, an iron-dependent form of nonapoptotic cell death mediated by lipid
peroxidation, has been implicated in the pathogenesis of multiple diseases. Subcellular …

Mitochondria are the primary source of energy production and are implicated in a wide
range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on …

Mitochondrial fission is a crucial process in maintaining metabolic homeostasis in normal
physiology and under conditions of stress. Its dysregulation has been associated with …

The metabolic patterns and energetics of human induced pluripotent stem cell-derived
cardiomyocytes (HiPSC-CMs) are much less than those of normal adult cardiomyocytes …

The intestinal tract is a target organ for Deoxynivalenol (DON) absorption and toxicity.
Mitochondrial homeostasis imbalance is the gut toxicity mechanism of DON. Lycopene …

Mitochondrion, known as the “powerhouse” of the cell, regulates ion homeostasis, redox
state, cell proliferation and differentiation, and lipid synthesis. The inner mitochondrial …

Endothelial cells (ECs), found in the innermost layer of blood vessels, are crucial for
maintaining the structure and function of coronary microcirculation. Dysregulated coronary …