The immunobiology of MIF: function, genetics and prospects for precision medicine
I Kang, R Bucala - Nature Reviews Rheumatology, 2019 - nature.com
The role of macrophage migration inhibitory factor (MIF) in autoimmunity is underscored by
data showing that common functional polymorphisms in MIF are associated with disease …
data showing that common functional polymorphisms in MIF are associated with disease …
Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus
JB Bilsborrow, E Doherty, PV Tilstam… - Expert opinion on …, 2019 - Taylor & Francis
Introduction. Macrophage migration inhibitory factor (MIF) is a pleiotropic inflammatory
cytokine with upstream regulatory roles in innate and adaptive immunity and is implicated in …
cytokine with upstream regulatory roles in innate and adaptive immunity and is implicated in …
MIF contribution to progressive brain diseases
Progressive brain diseases create a huge social and economic burden on modern societies
as a major cause of disability and death. Incidence of brain diseases has a significantly …
as a major cause of disability and death. Incidence of brain diseases has a significantly …
MIF: implications in the pathoetiology of systemic lupus erythematosus
T Lang, A Foote, JPW Lee, EF Morand… - Frontiers in …, 2015 - frontiersin.org
Macrophage migration Inhibitory factor (MIF) was one of the earliest pro-inflammatory
cytokines to be identified. Increasing interest in this cytokine in recent decades has followed …
cytokines to be identified. Increasing interest in this cytokine in recent decades has followed …
[HTML][HTML] Kv1. 3 channel-blocking immunomodulatory peptides from parasitic worms: implications for autoimmune diseases
The voltage-gated potassium (Kv) 1.3 channel is widely regarded as a therapeutic target for
immunomodulation in autoimmune diseases. ShK-186, a selective inhibitor of Kv1. 3 …
immunomodulation in autoimmune diseases. ShK-186, a selective inhibitor of Kv1. 3 …
[HTML][HTML] Macrophage migration inhibitory factor: a potential therapeutic target for rheumatoid arthritis
KW Kim, HR Kim - The Korean journal of internal medicine, 2016 - ncbi.nlm.nih.gov
Macrophage migration inhibitory factor (MIF) is originally identified in the culture medium of
activated T lymphocytes as a soluble factor that inhibits the random migration of …
activated T lymphocytes as a soluble factor that inhibits the random migration of …
Sinomenine regulates CD14/TLR4, JAK2/STAT3 pathway and calcium signal via α7nAChR to inhibit inflammation in LPS-stimulated macrophages
RL Zhu, YK Zhi, L Yi, JF Luo, J Li, SS Bai… - …, 2019 - Taylor & Francis
Objective: To investigate the cellular mechanism that sinomenine (SIN) inhibits inflammation
in macrophages induced by LPS through α7 nicotinic acetylcholine receptor (α7nAChR) …
in macrophages induced by LPS through α7 nicotinic acetylcholine receptor (α7nAChR) …
MIF promotes a differential Th1/Th2/Th17 inflammatory response in human primary cell cultures: Predominance of Th17 cytokine profile in PBMC from healthy subjects …
Abstract Macrophage migration Inhibitory Factor (MIF) is a cytokine associated with the
pathogenesis of autoimmune inflammatory diseases. There is evidence that MIF functions in …
pathogenesis of autoimmune inflammatory diseases. There is evidence that MIF functions in …
Deep Insight into the Role of MIF in Spondyloarthritis
B Wu, A Nakamura - Current Rheumatology Reports, 2022 - Springer
Abstract Purpose of Review Pathological roles of macrophage migration inhibitory factor
(MIF) have recently been demonstrated in spondyloarthritis (SpA) preclinical models …
(MIF) have recently been demonstrated in spondyloarthritis (SpA) preclinical models …
Macrophage migration inhibitory factor: association of− 794 CATT5–8 and− 173 G> C polymorphisms with TNF-α in systemic lupus erythematosus
Macrophage migration inhibitory factor (MIF) is an upstream immunoregulatory cytokine
associated with the pathogenesis of autoimmune inflammatory diseases. There is evidence …
associated with the pathogenesis of autoimmune inflammatory diseases. There is evidence …