The role of peroxisome proliferator-activated receptors in preeclampsia

I Psilopatis, K Vrettou, FN Fleckenstein, S Theocharis - Cells, 2023 - mdpi.com
Preeclampsia is a common pregnancy-related hypertensive disorder. Often presenting as
preexisting or new-onset hypertension complicated by proteinuria and/or end-organ …

Wild and cultivated olive trees: Nutraceutical insights of extra virgin olive oils in cardiovascular and ocular diseases

C Reyes-Goya, Á Santana-Garrido… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Extra virgin olive oil (EVOO) from Olea europaea (cultivated olive tree) and the oil obtained
from the wild olive variety or acebuche (ACE oil from Olea oleaster) contain an extraordinary …

Oxidative Regulation of Vascular Cav1.2 Channels Triggers Vascular Dysfunction in Hypertension-Related Disorders

XQ Hu, L Zhang - Antioxidants, 2022 - mdpi.com
Blood pressure is determined by cardiac output and peripheral vascular resistance. The L-
type voltage-gated Ca2+ (Cav1. 2) channel in small arteries and arterioles plays an …

Histopathological Clues of Enhanced Inflammation in the Placental Tissue of Women with Chronic Venous Disease in Lower Limbs during Pregnancy

MA Sánchez-Gil, O Fraile-Martinez… - Journal of Personalized …, 2024 - mdpi.com
It is estimated that approximately one in three women develop chronic venous disease
(CVD) during pregnancy, a broad spectrum of morphofunctional disorders affecting the …

The suppression of MAPK/NOX/MMP signaling prompts renoprotection conferred by prenatal naproxen in weaning preeclamptic rats

SA Abdelhady, MA Ali, DM Yacout, MM Essawy… - Scientific Reports, 2023 - nature.com
Although nonsteroidal antiinflammatory drugs (NSAIDs) are frequently used for fever and
pain during pregnancy, their possible interaction with perinatal renal injury induced by …

Evidence of increased oxidative stress in the placental tissue of women who suffered an episode of psychosis during pregnancy

MA Ortega, O Fraile-Martinez, C García-Montero… - Antioxidants, 2023 - mdpi.com
Psychosis is a complex clinical syndrome resulting in a loss of contact with reality and
alterations in behavior and sensorial and motor functions. Although the onset of psychosis …

[HTML][HTML] Identification of ferroptosis-related genes in syncytiotrophoblast-derived extracellular vesicles of preeclampsia

Q Wu, X Ying, W Yu, H Li, W Wei, X Lin, X Zhang - Medicine, 2022 - journals.lww.com
Preeclampsia (PE), defined as new-onset hypertension and multi-organ systemic
complication during pregnancy, is the leading cause of maternal and neonatal mortality and …

Proteomic Analysis Reveals Differential Protein Expression in Placental Tissues of Early-Onset Preeclampsia Patients

J Zhou, X Hu, N Zhang, Y Chu, J Wang… - Journal of Proteome …, 2024 - ACS Publications
Preeclampsia, a significant cause of maternal and perinatal morbidity and mortality, remains
poorly understood, in terms of its pathogenesis. This study aims to uncover novel and …

Mitochondrial ROS Accumulation Contributes to Maternal Hypertension and Impaired Remodeling of Spiral Artery but Not IUGR in a Rat PE Model Caused by …

J Long, Y Huang, G Wang, Z Tang, Y Shan, S Shen… - Antioxidants, 2023 - mdpi.com
Increased maternal glucocorticoid levels have been implicated as a risk factor for
preeclampsia (PE) development. We found that pregnant rats exposed to dexamethasone …

Non-invasive prediction of preeclampsia using the maternal plasma cell-free DNA profile and clinical risk factors

Y Yu, W Xu, S Zhang, S Feng, F Feng, J Dai… - Frontiers in …, 2024 - frontiersin.org
Background Preeclampsia (PE) is a pregnancy complication defined by new onset
hypertension and proteinuria or other maternal organ damage after 20 weeks of gestation …