Imidazole: An emerging scaffold showing its therapeutic Voyage to develop valuable molecular entities

B Chopra, AK Dhingra… - Current Drug Research …, 2020 - ingentaconnect.com
Objective: Imidazole is a heterocyclic moiety having immense biological importance. Since
ancient times, the imidazole nucleus is considered to be a promising moiety in the field of …

Synthesis of Analogues of Indole Alkaloids from Sea Sponges–Aplysinopsins by the Reaction of Amines with (4Z)‐4‐[(1H‐indol‐3‐yl)‐methylene]‐1, 3‐oxazol‐5 (4H) …

KF Suzdalev, MN Babakova - Journal of Heterocyclic …, 2016 - Wiley Online Library
A new two‐step approach toward the synthesis of aplysinopsin analogues 5‐(1‐R‐1H‐indol‐
3‐ylmethylene)‐2‐aryl‐3, 5‐dihydroimidazol‐4‐ones consisting in obtaining and reaction of …

Synthesis and Anticholinesterase Activity of [(4Z)-2-Aryl-4-(arylmethylidene)-5-oxo-4,5-dihydro-1H-imidazol-1-yl]alkanoic Acids

VO Topuzyan, VM Kazoyan, RA Tamazyan… - Russian Journal of …, 2018 - Springer
Abstract ω-[(4 Z)-2-Aryl-4-arylmethylidene-5-oxo-4, 5-dihydro-1 H-imidazol-1-yl] alkanoic
acids were synthesized by reaction of N-substituted α, β-dehydropeptides with chloro …

Microwave-assisted synthesis of new 2-aryl and 2-alkylimidazolones and evaluation of their in vitro anticancer activity and their in vivo toxicity on zebrafish embryos

S Bou Zeid, A Hamade, F Najjar, F Carreaux, S Eid - Chemical Papers, 2021 - Springer
Herein we describe the synthesis of five new 2-aryl and 2-alkylimidazolone derivatives via
an effective one-pot synthetic strategy assisted by microwave irradiations which allowed us …

[PDF][PDF] Synthesis, structure elucidation and antibacterial screening of some new 1, 3-imidazolinone derivatives using micro broth dilution assay

AN Hamad, RR Briem, SM Nooraddin… - ZANCO Journal of …, 2016 - researchgate.net
Some new 1, 3-imidazolinone derivatives have been readily prepared by the condensation
of oxazole-5-one derivatives (1 ai) with benzocaine in glacial acetic acid. The structures of …

Синтез и антихолинэстеразные свойства [(4Z)-2-арил-4-арилиден-5-оксо-4, 5-дигидро-1H-имидазол-1-ил] карбоновых кислот

ВО Топузян, ВМ Казоян, РА Тамазян… - Журнал органической …, 2018 - elibrary.ru
[(4Z)-2-Арил-4-арилиден-5-оксо-4, 5-дигидро-1Н-имидазол-1-ил] карбоновые кислоты
получены при взаимодействии N-замещенных α, β-дегидропептидов с …

[PDF][PDF] Novel synthesis of 3-(((E)-benzylidene) amino)-5-((Z)-3, 4-dimethoxybenzylidene)-2-phenyl-3, 5-dihydro-4H-imidazol-4-one derivatives as potent antimicrobial …

RB Manawar, MB Parmar, IJ Nayaka… - World Scientific …, 2019 - researchgate.net
Novel synthesis of 4H-imidazol-4-one derivative by reaction of (Z)-3-amino-5-(3, 4
dimethoxybenzylidene)-2-phenyl-3, 5-dihydro-4H-imidazol-4-one with derivative of different …

[PDF][PDF] Dr. PP Sharma, Dr. RP Pawar

SU Tekale - mgcollegearmori.ac.in
Synthesis ofsubstituted pyrazoles by one pot condensation reaction of substituted
cinnamaldehydes and tosylhydrazine in the presence of glyoxy; ic acid under solvent free …

Multifunctional Green Nanoporous Zeolites as Catalysts in Organic Synthesis

A Jain, R Tomar - Current Organocatalysis, 2018 - ingentaconnect.com
Background: The principal goal of this review is to provide a detailed study of various
modified zeolites as catalysts for the synthesis of diverse organic biologically active …

[PDF][PDF] Антимікробна активність та перспективи використання в медицині нових 5-карбофункціоналізованих імідазолів

ВК Свіжак - 2017 - dspace.vnmu.edu.ua
Обґрунтування вибору теми дослідження. Глобальне поширення
антибіотикорезистентності мікроорганізмів стало однією з найактуальніших проблем …