Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …

The identification of anti-NMDA receptor (NMDAR) encephalitis about 12 years ago made it
possible to recognise that some patients with rapidly progressive psychiatric symptoms or …

Encephalitis is a severe inflammatory disorder of the brain with many possible causes and a
complex differential diagnosis. Advances in autoimmune encephalitis research in the past …

Investigations in the last 10 years have revealed a new category of neurological diseases
mediated by antibodies against cell surface and synaptic proteins. There are currently 16 …

Autoantibodies are frequently observed in healthy individuals. In a minority of these
individuals, they lead to manifestation of autoimmune diseases, such as rheumatoid arthritis …

Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …

Anti-NMDA receptor (NMDAR) autoantibodies cause NMDAR encephalitis, the most
common autoimmune encephalitis, leading to psychosis, seizures, and autonomic …

N-Methyl-D-aspartate ionotropic glutamate receptors (NMDARs) play key roles in
synaptogenesis, synaptic maturation, long-term plasticity, neuronal network activity, and …

Background Anti-N-methyl-d-aspartate (NMDA) receptor encephalitis is a severe but
treatable autoimmune disorder which diagnosis depends on sensitive and specific antibody …

Anti-N-methyl D-aspartate receptor (NMDAR) encephalitis is a severe neuropsychiatric
disorder that associates with prominent memory and behavioural deficits. Patients' …