How to use COVID-19 antiviral drugs in patients with chronic kidney disease

A Kale, V Shelke, N Dagar, HJ Anders… - Frontiers in …, 2023 - frontiersin.org
Antiviral drugs such as Remdesivir (Veklury), Nirmatrelvir with Ritonavir (Paxlovid),
Azvudine, and Molnupiravir (Lagevrio) can reduce the risk for severe and fatal Coronavirus …

Sarilumab administration in COVID-19 patients: Literature review and considerations

A Marino, A Munafò, E Augello, CM Bellanca… - Infectious Disease …, 2022 - mdpi.com
Two years have passed since WHO declared a pandemic state for SARS-CoV-2 infection.
COVID-19 pathogenesis consists of a first viral phase responsible for early symptoms …

The role of IL-6 in TBI and PTSD, a potential therapeutic target?

M Monsour, DM Croci, S Agazzi - Clinical neurology and neurosurgery, 2022 - Elsevier
This literature review focuses on the role of IL-6 in TBI or PTSD-induced neuroinflammation.
While TBI and PTSD are widely prevalent, these diagnoses are particularly common …

A systematic review on the emergence of omicron variant and recent advancement in therapies

BM Konyak, M Sharma, S Kharia, RP Pandey… - Vaccines, 2022 - mdpi.com
With the ongoing COVID-19 pandemic, the emergence of the novel Omicron variant in
November 2021 has created chaos around the world. Despite mass vaccination, Omicron …

Efficacy of remdesivir and neutralizing monoclonal antibodies in monotherapy or combination therapy in reducing the risk of disease progression in elderly or …

DF Bavaro, L Diella, A Belati, G Metrangolo… - Viruses, 2023 - mdpi.com
Introduction: Remdesivir (REM) and monoclonal antibodies (mAbs) could alleviate severe
COVID-19 in at-risk outpatients. However, data on their use in hospitalized patients …

Infliximab as a potential treatment for COVID-19

MP Velez, MW McCarthy - Expert Review of Anti-infective Therapy, 2023 - Taylor & Francis
Introduction As the third year of the SARS-CoV-2 pandemic approaches, COVID-19
continues to cause substantial morbidity and mortality due to waning vaccine efficacy and …

TriTECM: A tetrafunctional T-cell engaging antibody with built-in risk mitigation of cytokine release syndrome

SC Carrara, J Harwardt, J Grzeschik, B Hock… - Frontiers in …, 2022 - frontiersin.org
Harnessing the innate power of T cells for therapeutic benefit has seen many shortcomings
due to cytotoxicity in the past, but still remains a very attractive mechanism of action for …

Drug-drug interactions between COVID-19 drug therapies and antidepressants

E Davoutis, C Panou, N Stachika, C Dalla… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Antidepressants are widely used for the pharmacological treatment of anxiety
and mood disorders. Since the eruption of the SARS-COV-2 pandemic and the later …

Adverse drug reactions associated with COVID-19 management

V Chavda, P Dodiya, V Apostolopoulos - … -Schmiedeberg's Archives of …, 2024 - Springer
The emergence of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)
outbreak, which causes COVID-19, had a devastating impact on both people's lives and the …

Effect of Anti-Interleukin-6 Agents on Psychopathology in a Sample of Patients with Post-COVID-19 Syndrome: An Observational Study

A Simonetti, A Restaino, E Bernardi, OM Ferrara… - Brain Sciences, 2024 - mdpi.com
Interleukin 6 (IL-6) receptor inhibitors tocilizumab and sarilumab have recently been
approved for severe coronavirus disease 2019 (COVID-19). They also affect mood, even …