Chiral molecules containing asymmetric carbon centers bonded with nitrogen are ubiquitous
in nature and also form important structural fragments in both natural and man-made …

Bisimine derivatives of salicylaldehyde with chiral diamines (salens) are privileged ligands
in asymmetric organometallic catalysis, which can be used in cooperation with …

Catalytic asymmetric cyanations of prochiral unsaturated compounds affording the
corresponding nitrile products in high enantiomeric excess (≥ 90% in general) are …

The addition of cyanide to a carbonyl compound to form a cyanohydrin is one of the
fundamental carbon-carbon bond forming reactions in organic chemistry1 and has …

Asymmetry is ubiquitous in every part of Nature1 and has a great impact in many fields, not
only in chemistry but also even in arts. In the pharmaceutical area, asymmetry plays an …

The chiral oxazaborolidinium salts 1 and 2 are excellent catalysts for the enantioselective
cyanosilylation of a wide variety of aldehydes (see Table 1) using trimethylsilyl (TMS) …

Chiral cyanohydrins are versatile building blocks for pharmaceuticals, agrochemicals and
specialty materials. A number of efficient and successful synthetic methods have been …

Dual activation by a chiral Lewis acid and an achiral or chiral Lewis base enabled cyanation
of both aromatic and aliphatic aldehydes with acetyl cyanide and ethyl cyanoformate to …

A μ-oxo-type chiral bis-Ti (IV) oxide (S, S)-1 can be successfully utilized in the asymmetric 1,
3-dipolar cycloaddition reactions between various nitrones 2 and acrolein to give the …

An aluminum complex was found to be high yielding and enantioselective for the addition of
cyanide to aldimines and ketimines. Although catalytic asymmetric addition of cyanide to …