The nutraceutical value of carnitine and its use in dietary supplements

A Durazzo, M Lucarini, A Nazhand, SB Souto, AM Silva… - Molecules, 2020 - mdpi.com
Carnitine can be considered a conditionally essential nutrient for its importance in human
physiology. This paper provides an updated picture of the main features of carnitine …

L-Carnitine alleviates hepatic and renal mitochondrial-dependent apoptotic progression induced by letrozole in female rats through modulation of Nrf-2, Cyt c and …

N Hassan, M Rashad, E Elleithy, Z Sabry… - Drug and Chemical …, 2023 - Taylor & Francis
Letrozole (LTZ) is a non-steroidal aromatase inhibitor that is commonly used in breast
cancer therapy. It has several side effects that might lead to the drug's cessation and data of …

Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS)-induced liver and kidney injury via inhibiting apoptosis, oxidative stress and …

X Zhang, C Su, S Zhao, J Li, F Yu - Bioengineered, 2022 - Taylor & Francis
Sepsis is a type of systemic inflammation response syndrome that leads to organ function
disorders. Currently, there is no specific medicine for sepsis in clinical practice …

Regulatory functions of L-Carnitine, acetyl, and propionyl L-Carnitine in a PCOS mouse model: focus on antioxidant/antiglycative molecular pathways in the ovarian …

G Di Emidio, F Rea, M Placidi, G Rossi, D Cocciolone… - Antioxidants, 2020 - mdpi.com
Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with female
infertility. Based on energy and antioxidant regulatory functions of carnitines, we …

The protective effect of L-carnitine on testosterone synthesis pathway, and spermatogenesis in monosodium glutamate-induced rats

F Koohpeyma, F Gholizadeh, H Hafezi… - … Medicine and Therapies, 2022 - Springer
Background Monosodium glutamate (MSG) is a food ingredient that is increasingly used
commercially. MSG leads to oxidative stress, consequently suppressing steroid hormone …

Acetyl-L-carnitine attenuates chronic ethanol-induced oxidative stress, ER stress and apoptosis in rat gastric tissue

H Er, A Gemici, GG Tas, L Sati, G Zengin, S Bilmen… - Alcohol, 2023 - Elsevier
Consuming alcohol affects almost all organs. Acetaldehyde, formed as the main product as
a result of alcohol metabolism, causes the production of free superoxide radicals when …

Acyl-Carnitines Exert Positive Effects on Mitochondrial Activity under Oxidative Stress in Mouse Oocytes: A Potential Mechanism Underlying Carnitine Efficacy on …

M Placidi, T Vergara, G Casoli, I Flati, D Capece… - Biomedicines, 2023 - mdpi.com
Carnitines play a key physiological role in oocyte metabolism and redox homeostasis. In
clinical and animal studies, carnitine administration alleviated metabolic and reproductive …

L-carnitine extenuates endocrine disruption, inflammatory burst and oxidative stress in carbendazim-challenged male rats via upregulation of testicular StAR and …

MA Salem, RS Ismail, HF Zaki, HMM Arafa… - Toxicology, 2021 - Elsevier
We have addressed in the current study the potential of L-carnitine (LC) to extenuate the
reproductive toxic insults of carbendazim (CBZ) in male rats, and the molecular mechanisms …

Diclofenac down-regulates COX-2 induced expression of CD44 and ICAM-1 in human HT29 colorectal cancer cells

Ç Yilmaz, S Köksoy, T Çeker, M Aslan - Naunyn-Schmiedeberg's archives …, 2021 - Springer
Abstract Cyclooxygenase-2 (COX-2) is expressed in a variety of human colorectal cancer
cells and can contribute to carcinogenesis. This study aimed to investigate the effect of …

Dietary supplementary glutamine and L-carnitine enhanced the anti-cold stress of Arbor Acres broilers

Y Liu, Y Yang, R Yao, Y Hu, P Liu, S Lian… - Archives Animal …, 2021 - aab.copernicus.org
Newborn poultry in cold regions often suffer from cold stress, causing a series of changes in
their physiology and metabolism, leading to slow growth and decreased production …