Melittin, the main venom component of the European Honeybee, is a cationic linear peptide-
amide of 26 amino acid residues with the sequence: GIGAVLKVLTTGLPALISWIKRKRQQ …

Although much progress has been achieved in the development of cancer therapies in
recent decades, problems continue to arise particularly with respect to chemotherapy due to …

Lipids are amphiphilic molecules, where one part of the molecule is water-loving
(hydrophilic) and the other water-hating (hydrophobic). When lipids are placed in contact …

The present study describes leucine zipper peptide–lipid hybrid nanoscale vesicles
engineered by self-assembled anchoring of the amphiphilic peptide within the lipid bilayer …

Since the development of bacterial resistance, the decreasing effectiveness of antibiotics is
becoming one of the most critical problems worldwide. Novel antibacterial agents are …

We developed a novel temperature-sensitive liposome, STL composed of 1, 2-dipalmitoyl-sn-
glycero-3-phosphocholine (DPPC), 1, 2-distearoyl-sn-glycero-3-phosphoethanolamine-N …

The pH low-insertion peptide (pHLIP) serves as a model system for peptide insertion and
folding across a lipid bilayer. It has three general states:(I) soluble in water or (II) bound to …

Poor tumor selectivity and short life span of reactive oxygen species (ROS) are two major
challenges in photodynamic therapy (PDT). In this study, a self‐transformable pH‐driven …

We find that pH-(low)-insertion-peptide (pHLIP)-facilitated translocation of phalloidin, a cell-
impermeable polar toxin, inhibits the proliferation of cancer cells in a pH-dependent fashion …

Acidity is a biomarker of cancer that is not subject to the blunting clonal selection effects that
reduce the efficacy of other biomarker technologies, such as antibody targeting. The pH …