Importance Osteoarthritis (OA) is the most common joint disease, affecting an estimated
more than 240 million people worldwide, including an estimated more than 32 million in the …

Musculoskeletal pain conditions are age-related, leading contributors to chronic pain and
pain-related disability, which are expected to rise with the rapid global population aging …

Importance Primary care clinicians find managing chronic pain challenging. Evidence of
long-term efficacy of opioids for chronic pain is limited. Opioid use is associated with serious …

Opioid Abuse in Chronic Pain — Misconceptions and Mitigation Strategies | New England Journal
of Medicine Skip to main content The New England Journal of Medicine homepage Advanced …

Pain is the predominant symptom for people with inflammatory arthritis (IA) and osteoarthritis
(OA) mandating the development of evidence-based recommendations for the health …

Objective To determine the clinical effectiveness of common elective orthopaedic
procedures compared with no treatment, placebo, or non-operative care and assess the …

Objective To investigate the efficacy and safety of paracetamol (acetaminophen) in the
management of spinal pain and osteoarthritis of the hip or knee. Design Systematic review …

The objective was to develop evidence-based recommendations and a research and
educational agenda for the non-pharmacological management of hip and knee osteoarthritis …

Purpose Although a number of osteoarthritis (OA) management guidelines exist, uptake has
been suboptimal. Our aim was to review and critically evaluate existing OA management …

Abstract Objective To update the American College of Rheumatology (ACR) 2000
recommendations for hip and knee osteoarthritis (OA) and develop new recommendations …