This review gives an overview of enzymatic reactions that have been conducted on
substrates attached to solid surfaces. Such biochemical reactions have become more …

The purpose of the present study was to analyse mutations in the gyrA and gyrB genes of
Mycobacterium tuberculosis and define the possible correlation between these mutations …

Background The aim of this study was to identify mutations of r poB, katG, inhA and ahp-
genes associated Mycobacterium tuberculosis resistance to rifampicin (RIF) and isoniazid …

Despite enormous progress, tuberculosis (TB) is still a major global health problem. Poor
patients' adherence to the current treatment leads to the emergence of multidrug resistant …

A microarray analyzer was developed to obtain images and measure the fluorescence
intensity of microarrays at three wavelengths from 380 nm to 850 nm. The analyzer contains …

Background The steady rise in the spread of multidrug-resistant tuberculosis (MDR-TB) and
extensively drug-resistant tuberculosis (XDR-TB) requires rapid and reliable methods to …

Background Nucleic acid amplification tests are widely used in TB diagnostics. Priority tasks
in their development consist of increasing the specificity and sensitivity of the detection of …

A simple approach to fabricating hydrogel-based DNA microarrays is reported by physically
entrapping the rolling circle amplification (RCA) product inside printable in situ gelling …

In addition to the obligatory pathogenic species of the Mycobacterium tuberculosis complex
and Mycobacterium leprae, the genus Mycobacterium also includes conditionally …

Mycobacterium tuberculosis remains a leading cause of morbidity and mortality worldwide.
This circumstance underscores the relevance of population studies of tuberculosis for …