AmpC β-lactamases are clinically important cephalosporinases encoded on the
chromosomes of many of the Enterobacteriaceae and a few other organisms, where they …

Unfortunately for mankind, it is very likely that the antibiotic resistance problem we have
generated during the last 60 years due to the extensive use and misuse of antibiotics is here …

Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases and AmpC
β-lactamases) have been frequently demonstrated in the microbiota of food-producing …

This review deeply addresses for the first time the diversity, regulation and mechanisms
leading to mutational overexpression of intrinsic β-lactamases from non-fermenting and …

It is generally accepted that resistance genes acquired by human pathogens through
horizontal gene transfer originated in environmental, non-pathogenic bacteria. As a …

Aeromonas hydrophila is a pathogenic bacterium that has been implicated in fish, animal,
and human disease. Recently, a multidrug resistance (MDR) plasmid, pR148, was isolated …

Resistance to various classes of antimicrobial agents has been encountered in many
bacteria of medical and veterinary relevance. Particular attention has been paid to zoonotic …

This study investigated the ecology, epidemiology and plasmid characteristics of extended-
spectrum cephalosporin (ESC)-resistant E. coli in healthy pigs over a period of 4 years …

Early after the introduction of the first (narrow spectrum) penicillins into clinical use,
penicillinase-producing staphylococci replaced (worldwide) the previously susceptible …

Mutations within the structural gene of ampD can lead to AmpC overproduction and
increases in β-lactam MICs in organisms with an inducible ampC. However, identification of …