Current trends and challenges in cancer management and therapy using designer nanomaterials

PN Navya, A Kaphle, SP Srinivas, SK Bhargava… - Nano convergence, 2019 - Springer
Nanotechnology has the potential to circumvent several drawbacks of conventional
therapeutic formulations. In fact, significant strides have been made towards the application …

Novel epirubicin-loaded nanoformulations: Advancements in polymeric nanocarriers for efficient targeted cellular and subcellular anticancer drug delivery

M Pourmadadi, S Ostovar, G Ruiz-Pulido… - Inorganic Chemistry …, 2023 - Elsevier
Cancer affects millions of people worldwide, and it is projected that there will be 1,958,310
new cancer cases and 609,820 cancer fatalities in the United States in 2023. Epirubicin …

Meta-analysis of nanoparticle delivery to tumors using a physiologically based pharmacokinetic modeling and simulation approach

YH Cheng, C He, JE Riviere, NA Monteiro-Riviere… - ACS …, 2020 - ACS Publications
Numerous studies have engineered nanoparticles with different physicochemical properties
to enhance the delivery efficiency to solid tumors, yet the mean and median delivery …

Environmental stimulus-responsive mesoporous silica nanoparticles as anticancer drug delivery platforms

H Zhao, Y Li, J Chen, J Zhang, Q Yang, J Cui… - Colloids and Surfaces B …, 2024 - Elsevier
Currently, cancer poses a significant health challenge in the medical community. Traditional
chemotherapeutic agents are often accompanied by toxic side effects and limited …

Mesoporous silica nanoparticles: Synthesis and multifaceted functionalization for controlled drug delivery

J Gupta, M Quadros, M Momin - Journal of Drug Delivery Science and …, 2023 - Elsevier
Inorganic mesoporous silica nanoparticles (MSN) are porous materials extensively studied
for drug delivery due to their properties such as facile and diverse synthesis methods …

Trends in targeted delivery of nanomaterials in colon cancer diagnosis and treatment

FA Khan, R Albalawi, FH Pottoo - Medicinal research reviews, 2022 - Wiley Online Library
Colon cancer is an adenocarcinoma, which subsequently develops into malignant tumors, if
not treated properly. The current colon cancer therapy mainly revolves around …

Hybrid system for local drug delivery and magnetic hyperthermia based on SPIONs loaded with doxorubicin and epirubicin

D Nieciecka, J Celej, M Żuk, A Majkowska-Pilip… - Pharmaceutics, 2021 - mdpi.com
Cancer is one of the most common causes of death worldwide, thus new solutions in
anticancer therapies are highly sought after. In this work, superparamagnetic iron oxide …

Improving anti-cancer drug delivery performance of magnetic mesoporous silica nanocarriers for more efficient colorectal cancer therapy

S Iranpour, AR Bahrami, S Nekooei… - Journal of …, 2021 - Springer
Background Improving anti-cancer drug delivery performance can be achieved through
designing smart and targeted drug delivery systems (DDSs). For this aim, it is important to …

Application of smart nanoparticles as a potential platform for effective colorectal cancer therapy

S Iranpour, AR Bahrami, AS Saljooghi… - Coordination Chemistry …, 2021 - Elsevier
Nowadays, nanomedicine has emerged as one of the most interesting fields of biomedical
research, combining nanotechnology and medicine to offer a better prospect to design …

Enhanced theranostic efficacy of epirubicin-loaded SPION@ MSN through co-delivery of an anti-miR-21-expressing plasmid and ZIF-8 hybridization to target colon …

A Abrishami, AR Bahrami, AS Saljooghi, MM Matin - Nanoscale, 2024 - pubs.rsc.org
Using targeted drug delivery systems has emerged as a promising approach to increase the
efficacy of chemotherapy, particularly in combination with gene therapy. The overexpression …