Current developments of coumarin compounds in medicinal chemistry

XM Peng, G LV Damu, H Zhou - Current pharmaceutical …, 2013 - ingentaconnect.com
Coumarin compounds represent an important type of naturally occurring and synthetic
oxygen-containing heterocycles with typical benzopyrone framework. This type of special …

Botanical sources, chemistry, analysis, and biological activity of furanocoumarins of pharmaceutical interest

R Bruni, D Barreca, M Protti, V Brighenti, L Righetti… - Molecules, 2019 - mdpi.com
The aim of this work is to provide a critical review of plant furanocoumarins from different
points of view, including their chemistry and biosynthetic pathways to their extraction …

Implication of coumarins towards central nervous system disorders

K Skalicka-Woźniak, IE Orhan, GA Cordell… - Pharmacological …, 2016 - Elsevier
Coumarins are widely distributed, plant-derived, 2 H-1-benzopyran-2-one derivatives which
have attracted intense interest in recent years as a result of their diverse and potent …

Non-alkaloid cholinesterase inhibitory compounds from natural sources

AN Tamfu, S Kucukaydin, B Yeskaliyeva, M Ozturk… - Molecules, 2021 - mdpi.com
Alzheimer's disease (AD) is a severe neurodegenerative disorder of different brain regions
accompanied by distresses and affecting more than 25 million people in the world. This …

Natural inhibitors of cholinesterases: chemistry, structure–activity and methods of their analysis

N Smyrska-Wieleba, T Mroczek - International Journal of Molecular …, 2023 - mdpi.com
This article aims to provide an updated description and comparison of the data currently
available in the literature (from the last 15 years) on the studied natural inhibitors of …

Imperatorin: a review of its pharmacology, toxicity and pharmacokinetics

M Deng, L Xie, L Zhong, Y Liao, L Liu, X Li - European Journal of …, 2020 - Elsevier
As a naturally occurring furanocoumarin, the medicinal value of imperatorin has been
studied more and more. We hope to provide useful information for the further development of …

Understanding the phytochemistry and molecular insights to the pharmacology of Angelica archangelica L. (garden angelica) and its bioactive components

A Kaur, R Bhatti - Phytotherapy research, 2021 - Wiley Online Library
Plant‐derived molecules have enduring usefulness in treating diseases, and herbal drugs
have emerged as a vital component of global therapeutic demand. Angelica archangelica …

Nature as a source of metabolites with cholinesterase-inhibitory activity: an approach to Alzheimer's disease treatment

BR Pinho, F Ferreres, P Valentão… - Journal of Pharmacy …, 2013 - academic.oup.com
Objectives Alzheimer's disease (AD) is the most common cause of dementia, being
responsible for high healthcare costs and familial hardships. Despite the efforts of …

Quantitative analysis of phenolic metabolites from different parts of Angelica keiskei by HPLC–ESI MS/MS and their xanthine oxidase inhibition

DW Kim, MJ Curtis-Long, HJ Yuk, Y Wang, YH Song… - Food chemistry, 2014 - Elsevier
Angelica keiskei is used as popular functional food stuff. However, quantitative analysis of
this plant's metabolites has not yet been disclosed. The principal phenolic compounds (1 …

Quality control of traditional Chinese medicines: a review

S Xin-Yue, LI Ying-Dong, SHI Yan-Ping, JIN Ling… - Chinese Journal of …, 2013 - Elsevier
Abstract Traditional Chinese medicines (TCMs) are in great demand all over the world,
especially in the developing world, for primary health care due to their superior merits such …