The development and spread of resistance to antimalarial drugs poses a severe and
increasing public health threat. Failures of prophylaxis or treatment with quinolines …

Chloroquine (CQ) has been the front line antimalarial drug due to its efficacy, low cost and
scanty side effects, until resistance has evolved. Although its use has been officially …

Background The initial global outbreak of the novel coronavirus disease 2019 (COVID-
2019) pandemic, which is responsible for the severe acute respiratory syndrome 2 (SARS …

We evaluated gametocyte carriage and intensities of gametocytaemia in 710 children
presenting with acute, symptomatic, uncomplicated Plasmodium falciparum malaria who …

Plasmodium falciparum is one of the most lethal parasite responsible for human malaria.
Until now, the only one solution to counter malaria is the use of antimalarial drugs …

Background: The initial global outbreak of the novel coronavirus disease 2019 (COVID-
2019) pandemic, responsible for the severe acute respiratory syndrome 2 (SARS-CoV-2) …

We evaluated the causal prophylactic antimalarial activity of a single oral dose of
pafuramidine (DB289), an experimental prodrug of active metabolite DB75, in a randomized …

One hundred and eight children with acute, symptomatic, uncomplicated, falciparum malaria
were randomized to receive chloroquine (for 3 days) plus chlorpheniramine alone (for seven …

The emergence and spread of antiparasitic drug resistance pose a severe and increasing
public health threat. Failures in prophylaxis or those in treatment with quinolines …

Malaria and HIV/AIDS remain diseases of public health importance in sub-Saharan Africa as
both infections are responsible for high morbidity and mortality rates. Malaria …